Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 4/20 | 0.41 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9725475 | 0.98 | CCR4 (0.42) | CCR4LMNACYP1A2MEN1KMT2A | |
| SCHEMBL9725424 | 0.86 | CCR4 (0.50) | CCR4LMNACYP1A2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9725372 | 0.85 | CCR4 (0.49) | CCR4LMNACYP1A2MEN1KMT2A | |
| SCHEMBL9725430 | 0.82 | MPO (0.45) | CCR4CYP1A2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9725470 | 0.82 | MPO (0.45) | CCR4LMNACYP1A2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9725529 | 0.81 | MPO (0.44) | CCR4CYP1A2MEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9725446 | 0.81 | MPO (0.44) | CCR4LMNACYP1A2MEN1KMT2A | |
| SCHEMBL9725374 | 0.79 | DAO (0.36) | CCR4CYP1A2SMN1; SMN2MPOHAVCR2 | |
| SCHEMBL9725479 | 0.79 | CCR4 (0.56) | CCR4LMNACYP1A2MEN1KMT2A | |
| SCHEMBL7063351 | 0.79 | CYP1A2 (0.65) | LMNACYP1A2MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162318-A | Which have pulmonary surfactant secretion promoting activity | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0454330-A1 | Benzimidazolinone derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-10-30 | — | — | EP | disclosed |