Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 3/20 | 0.35 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | CCR4 | P51679 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | WEE1 | P30291 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9725534 | 0.99 | DAO (0.35) | DAOCSNK2A2CSNK2BCSNK2A1MPO | |
| SCHEMBL9725387 | 0.83 | DAO (0.36) | DAOMPOHAVCR2PDE4APDE4B | |
| Hydrochloric Acid SCHEMBL9725460 | 0.82 | DAO (0.35) | DAOMPOHAVCR2PDE4APDE4B | |
| SCHEMBL9725356 | 0.79 | CCR4 (0.43) | DAOMPOHAVCR2CCR4SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9725475 | 0.78 | CCR4 (0.42) | DAOMPOHAVCR2CCR4SMN1; SMN2 | |
| SCHEMBL9725424 | 0.73 | CCR4 (0.50) | MPOCCR4KDM4ESMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9725372 | 0.72 | CCR4 (0.49) | MPOCCR4KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL9725430 | 0.71 | MPO (0.45) | MPOHAVCR2CCR4SMN1; SMN2CYP1A2 | |
| SCHEMBL9725470 | 0.71 | MPO (0.45) | MPOHAVCR2CCR4SIGMAR1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9725529 | 0.70 | MPO (0.44) | MPOHAVCR2CCR4SIGMAR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162318-A | Which have pulmonary surfactant secretion promoting activity | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0454330-A1 | Benzimidazolinone derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-10-30 | — | — | EP | disclosed |