Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL221825 | 0.74 | SLC9A1 (0.41) | ADORA2AADORA2BADORA3ADORA1ALDH1A1 | |
| 5-Bromouracil SCHEMBL28330235 | 0.73 | ATAD2 (0.36) | ALDH1A1LMNAMAPTTSHRPMP22 | |
| SCHEMBL11480635 | 0.73 | ADORA2A (0.36) | ADORA2AADORA2BADORA3ADORA1ALDH1A1 | |
| SCHEMBL28179392 | 0.73 | FEN1 (0.31) | — | |
| SCHEMBL9685966 | 0.73 | ALDH1A1 (0.37) | ADORA2AADORA2BADORA3ADORA1ALDH1A1 | |
| SCHEMBL8167544 | 0.73 | TDP1 (0.38) | ALDH1A1 | |
| SCHEMBL2078821 | 0.73 | ADORA2A (0.36) | ADORA2AADORA2BADORA3ADORA1ALDH1A1 | |
| SCHEMBL25979874 | 0.73 | ADORA2A (0.36) | ADORA2AADORA2BADORA3ADORA1ALDH1A1 | |
| SCHEMBL27423099 | 0.72 | ADORA2A (0.33) | ADORA2AADORA2BADORA3ADORA1ALDH1A1 | |
| SCHEMBL11723298 | 0.72 | ALDH1A1 (0.35) | ADORA2BALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119662655-A | Application of RNA molecule and composition thereof in tumor immunotherapy | 武汉厚先生物医药有限公司 | 2025-03-21 | — | — | CN | disclosed |
| WO-2023220428-A1 | COMPOSITIONS FOR EDITING ASS1 TRANSCRIPTS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023220440-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |
| CN-116916936-A | Compositions and methods for delivering RNA | 再生技术有限责任公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-116425682-A | Pyrimidine-1 (2H) -oxo compound and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-07-14 | — | — | CN | disclosed |
| EP-3708566-B1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2023-02-08 | — | — | EP | disclosed |
| CN-115515559-A | Rectal delivery of messenger RNA | 翻译生物公司 | 2022-12-23 | — | — | CN | disclosed |
| CN-107428744-B | Novel heterocyclic compounds and their use in medicine and cosmetics | 盖尔德马研究及发展公司 | 2021-09-24 | — | — | CN | disclosed |
| EP-3708566-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2020-09-16 | — | — | EP | disclosed |
| EP-3237403-B1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2020-05-06 | — | — | EP | disclosed |
| US-10246422-B2 | Heterocyclic compounds and use thereof in medicine and in cosmetics | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2019-04-02 | — | — | US | disclosed |
| EP-2875006-B1 | ACID CERAMIDASE INHIBITORS AND THEIR USE AS MEDICAMENTS | FONDAZIONE ST ITALIANO TECNOLOGIA (IT) | 2018-12-26 | — | — | EP | disclosed |
| US-20180050992-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND USE THEREOF IN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2018-02-22 | — | — | US | disclosed |
| US-9428465-B2 | Acid ceramidase inhibitors and their use as medicaments | FONDAZIONE ISTITUTO ITALIANO DI TECHNOLOGIA (IT) | 2016-08-30 | — | — | US | disclosed |
| US-20150111892-A1 | ACID CERAMIDASE INHIBITORS AND THEIR USE AS MEDICAMENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150111892-A1 | ACID CERAMIDASE INHIBITORS AND THEIR USE AS MEDICAMENTS | ASAH1, ASAH2, ACER2 | ADORA2A 3419/4885ADORA2B 2076/4885ADORA3 2330/4885 |
| US-20180050992-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND USE THEREOF IN MEDICINE AND IN COSMETICS | MC1R, CALCRL, BDKRB2 | ADORA2A 377/4885ADORA2B 346/4885ADORA3 243/4885 |
| US-10246422-B2 | Heterocyclic compounds and use thereof in medicine and in cosmetics | MC1R, BDKRB2, CCKBR | ADORA2A 381/4885ADORA2B 326/4885ADORA3 251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.