SCHEMBL17870701

SCHEMBL17870701

O=C(O)Nc1ccccc1C(=O)N(Cc1ccccc1)C1CCNCC1

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DCUN1D1 Q96GG9 1/20 0.51
SLC6A2 P23975 8/20 0.45
SLC6A4 P31645 8/20 0.45
SLC6A3 Q01959 6/20 0.45
MAPT P10636 1/20 0.44
AGER Q15109 3/20 0.44
MTNR1A P48039 1/20 0.44
CHRM2 P08172 1/20 0.44
CHRM3 P20309 1/20 0.44
KCNH2 Q12809 4/20 0.43
ABCC1 P33527 1/20 0.41
GAA P10253 1/20 0.41
KCNA5 P22460 1/20 0.41
C5AR1 P21730 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5744569 0.83 DCUN1D1 (0.52) DCUN1D1SLC6A2SLC6A4SLC6A3MAPT
SCHEMBL3811903 0.80 DCUN1D1 (0.58) DCUN1D1SLC6A2SLC6A4SLC6A3AGER
Hydrochloric Acid SCHEMBL21410210 0.79 DCUN1D1 (0.57) DCUN1D1SLC6A2SLC6A4SLC6A3AGER
SCHEMBL2959297 0.76 DCUN1D1 (0.75) DCUN1D1
SCHEMBL6622412 0.75 DCUN1D1 (0.54) DCUN1D1SLC6A2SLC6A4SLC6A3AGER
SCHEMBL619150 0.75 SLC6A2 (0.71) DCUN1D1SLC6A2SLC6A4SLC6A3AGER
SCHEMBL6633233 0.75 DCUN1D1 (0.60) DCUN1D1SLC6A2SLC6A4SLC6A3AGER
SCHEMBL2233149 0.74 AGER (0.58) DCUN1D1SLC6A2SLC6A4SLC6A3AGER
SCHEMBL2233154 0.74 AGER (0.58) DCUN1D1SLC6A2SLC6A4SLC6A3AGER
Hydrochloric Acid SCHEMBL22797899 0.74 SLC6A2 (0.70) DCUN1D1SLC6A2SLC6A4SLC6A3AGER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3237403-A1 NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS Galderma Research & Development (FR) 2017-11-01 EP disclosed
WO-2016102882-A1 NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS GALDERMA RESEARCH & DEVELOPMENT (FR) 2016-06-30 WO disclosed