Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 3/20 | 0.43 |
| ▸ | AGER | Q15109 | 3/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19027674 | 0.90 | OPRM1 (0.50) | DCUN1D1OPRM1AGERMTNR1ACHRM2 | |
| SCHEMBL3811903 | 0.87 | DCUN1D1 (0.58) | DCUN1D1SLC6A2SLC6A4SLC6A3KCNH2 | |
| Hydrochloric Acid SCHEMBL21410210 | 0.85 | DCUN1D1 (0.57) | DCUN1D1SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL16118655 | 0.85 | HTR2A (0.59) | DCUN1D1SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL2959297 | 0.85 | DCUN1D1 (0.75) | DCUN1D1 | |
| SCHEMBL619150 | 0.84 | SLC6A2 (0.71) | DCUN1D1SLC6A2SLC6A4SLC6A3KCNH2 | |
| Hydrochloric Acid SCHEMBL22797899 | 0.83 | SLC6A2 (0.70) | DCUN1D1SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL16118653 | 0.83 | DCUN1D1 (0.56) | DCUN1D1SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL19027677 | 0.82 | OPRM1 (0.54) | DCUN1D1OPRM1CHRM2CHRM3 | |
| SCHEMBL16118658 | 0.82 | DCUN1D1 (0.55) | DCUN1D1SLC6A2SLC6A4SLC6A3AGER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417202-A2 | AMINOPIPERIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2004-05-12 | — | — | EP | disclosed |
| US-20030069276-A1 | Amino piperidine derivatives | F.HOFFMANN-LA ROCHE AG (CH) | 2003-04-10 | — | — | US | disclosed |
| WO-2002079186-A2 | AMINOPIPERIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2002-10-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069276-A1 | Amino piperidine derivatives | CCR5, CCR2, CXCR4 | DCUN1D1 3697/4885SLC6A2 2830/4885SLC6A4 1811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.