Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17870736 | 1.00 | ALDH1A1 (0.43) | ALDH1A1SIGMAR1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL19873972 | 0.83 | SIGMAR1 (0.39) | ALDH1A1SIGMAR1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL17870796 | 0.83 | SIGMAR1 (0.52) | ALDH1A1SIGMAR1SMN1; SMN2LMNARAB9A | |
| SCHEMBL17870798 | 0.83 | SIGMAR1 (0.52) | ALDH1A1SIGMAR1SMN1; SMN2LMNARAB9A | |
| SCHEMBL17870745 | 0.82 | CYP2C19 (0.37) | ALDH1A1SIGMAR1RAB9ACYP2C19KMT2A | |
| SCHEMBL3958147 | 0.78 | HTT (0.44) | ALDH1A1LMNATDP1RAB9AL3MBTL1 | |
| SCHEMBL1813803 | 0.76 | ALDH1A1 (0.55) | ALDH1A1SIGMAR1KDM4ERAB9AL3MBTL1 | |
| SCHEMBL1813802 | 0.76 | ALDH1A1 (0.55) | ALDH1A1SIGMAR1KDM4ERAB9AL3MBTL1 | |
| SCHEMBL27644978 | 0.76 | RAB9A (0.44) | ALDH1A1SIGMAR1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL23236146 | 0.72 | DPP4 (0.44) | ALDH1A1SMN1; SMN2LMNATDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3708566-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2020-09-16 | — | — | EP | disclosed |
| EP-3237403-B1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2020-05-06 | — | — | EP | disclosed |
| EP-3237403-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2017-11-01 | — | — | EP | disclosed |
| WO-2016102882-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2016-06-30 | — | — | WO | disclosed |