Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | GNRHR | P30968 | 6/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.33 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30178348 | 0.86 | GNRHR (0.41) | MALT1DRD2IDO1TDP1SCN9A | |
| SCHEMBL17870723 | 0.86 | GNRHR (0.41) | MALT1DRD2IDO1TDP1SCN9A | |
| SCHEMBL28660744 | 0.83 | GNRHR (0.40) | MALT1DRD2IDO1SCN9AGNRHR | |
| SCHEMBL19873836 | 0.83 | DRD2 (0.36) | MALT1DRD2IDO1SCN9AGNRHR | |
| SCHEMBL30178472 | 0.83 | DRD2 (0.36) | MALT1DRD2IDO1SCN9AGNRHR | |
| SCHEMBL17870711 | 0.80 | IDO1 (0.43) | MALT1DRD2IDO1SCN9A | |
| SCHEMBL17870795 | 0.76 | DRD2 (0.44) | MALT1DRD2TDP1GNRHRCYP3A4 | |
| SCHEMBL30178350 | 0.76 | DRD2 (0.44) | MALT1DRD2TDP1GNRHRCYP3A4 | |
| SCHEMBL28639211 | 0.74 | DRD2 (0.43) | MALT1DRD2GNRHRCYP3A4MEN1 | |
| SCHEMBL19873832 | 0.74 | DRD2 (0.43) | MALT1DRD2GNRHRCYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3237403-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2017-11-01 | — | — | EP | disclosed |
| WO-2016102882-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2016-06-30 | — | — | WO | disclosed |