Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 10/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 10/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 10/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 10/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19747069 | 1.00 | MEN1 (0.44) | MEN1KMT2AALDH1A1DRD2DRD4 | |
| SCHEMBL17870863 | 0.82 | PIK3CD (0.42) | ALDH1A1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL17870841 | 0.82 | PIK3CD (0.42) | ALDH1A1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL5545260 | 0.80 | TNKS (0.44) | MEN1KMT2AALDH1A1CHRM2CHRM4 | |
| SCHEMBL5545264 | 0.80 | TNKS (0.44) | MEN1KMT2AALDH1A1CHRM2CHRM4 | |
| SCHEMBL19746550 | 0.78 | CCR5 (0.45) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL6516854 | 0.76 | KMT2A (0.46) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL6516859 | 0.76 | KMT2A (0.46) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL19748971 | 0.76 | CCR5 (0.46) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL17870854 | 0.75 | CCR5 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3471718-A1 | PURIFIED CENICRIVIROC AND PURIFIED INTERMEDIATES FOR MAKING CENICRIVIROC | Tobira Therapeutics, Inc. (US) | 2019-04-24 | — | — | EP | claimed |
| WO-2017223155-A1 | PURIFIED CENICRIVIROC AND PURIFIED INTERMEDIATES FOR MAKING CENICRIVIROC | TOBIRA THERAPEUTICS, INC. (US) | 2017-12-28 | — | — | WO | claimed |
| EP-3237424-A1 | PROCESS OF MAKING CENICRIVIROC AND RELATED ANALOGS | Tobira Therapeutics, Inc. (US) | 2017-11-01 | — | — | EP | claimed |
| WO-2016105527-A1 | PROCESS OF MAKING CENICRIVIROC AND RELATED ANALOGS | TOBIRA THERAPEUTICS, INC. (US) | 2016-06-30 | — | — | WO | claimed |
| EP-3237424-A1 | PROCESS OF MAKING CENICRIVIROC AND RELATED ANALOGS | Tobira Therapeutics, Inc. (US) | 2017-11-01 | — | — | EP | disclosed |
| WO-2016105527-A1 | PROCESS OF MAKING CENICRIVIROC AND RELATED ANALOGS | TOBIRA THERAPEUTICS, INC. (US) | 2016-06-30 | — | — | WO | disclosed |