Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.68 |
| ▸ | TP53 | P04637 | 6/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.68 |
| ▸ | HTT | P42858 | 4/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.68 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | MPI | P34949 | 1/20 | 0.68 |
| ▸ | ATM | Q13315 | 1/20 | 0.68 |
| ▸ | BCHE | P06276 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2237500 | 0.99 | BCHE (0.67) | KDM4EL3MBTL1TP53ALOX15ALOX12 | |
| Hydrochloric Acid SCHEMBL19437125 | 0.97 | BCHE (0.66) | KDM4EL3MBTL1TP53ALOX15ALOX12 | |
| SCHEMBL26241625 | 0.93 | BCHE (0.74) | KDM4EL3MBTL1TP53ALOX15ALOX12 | |
| SCHEMBL1240756 | 0.86 | BCHE (0.63) | KDM4EL3MBTL1TP53ALOX15ALOX12 | |
| SCHEMBL26241636 | 0.86 | BCHE (0.70) | KDM4EL3MBTL1TP53ALOX15ALOX12 | |
| SCHEMBL12530883 | 0.85 | BCHE (0.62) | KDM4EL3MBTL1TP53ALOX15ALOX12 | |
| SCHEMBL9976030 | 0.85 | BCHE (0.69) | KDM4EL3MBTL1TP53ALOX15ALOX12 | |
| SCHEMBL16825209 | 0.82 | KDM4E (0.58) | KDM4EL3MBTL1TP53ALOX15ALOX12 | |
| SCHEMBL17223776 | 0.82 | KDM4E (0.65) | KDM4EL3MBTL1TP53ALOX15ALOX12 | |
| SCHEMBL19437093 | 0.82 | KDM4E (0.54) | KDM4EL3MBTL1TP53ALOX15ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3137079-A1 | INHIBITORS OF JMJD2C AS ANTICANCER AGENTS | The J. David Gladstone Institutes (US) | 2017-03-08 | — | — | EP | claimed |
| US-20170044107-A1 | Inhibitors of JMJD2C as Anticancer Agents | THE J. DAVID GLADSTONE INSTITUTES | 2017-02-16 | — | — | US | claimed |
| WO-2015167874-A1 | INHIBITORS OF JMJD2C AS ANTICANCER AGENTS | THE J. DAVID GLADSTONE INSTITUTES (US) | 2015-11-05 | — | — | WO | claimed |
| EP-3440070-B1 | MDR-REVERSING 8-HYDROXY-QUINOLINE DERIVATIVES | MTA TERMESZETTUDOMANYI KUTATOKOEZPONT (HU) | 2024-10-30 | — | — | EP | disclosed |
| EP-3137079-A1 | INHIBITORS OF JMJD2C AS ANTICANCER AGENTS | The J. David Gladstone Institutes (US) | 2017-03-08 | — | — | EP | disclosed |
| US-20170044107-A1 | Inhibitors of JMJD2C as Anticancer Agents | THE J. DAVID GLADSTONE INSTITUTES | 2017-02-16 | — | — | US | disclosed |
| WO-2015167874-A1 | INHIBITORS OF JMJD2C AS ANTICANCER AGENTS | THE J. DAVID GLADSTONE INSTITUTES (US) | 2015-11-05 | — | — | WO | disclosed |
| US-9012899-B2 | Electroluminescent metal complexes with nucleophilic carbene ligands | BASF SE (DE) | 2015-04-21 | — | — | US | disclosed |
| US-20130292660-A1 | ELECTROLUMINESCENT METAL COMPLEXES WITH NUCLEOPHILIC CARBENE LIGANDS | BASF SE (DE) | 2013-11-07 | — | — | US | disclosed |
| US-8492749-B2 | Electroluminescent metal complexes with nucleophilic carbene ligands | BASF SE (DE) | 2013-07-23 | — | — | US | disclosed |
| US-20120196853-A1 | Novel Quinoline-Hepcidine Antagonists | VIFOR (INTERNATIONAL) AG (CH) | 2012-08-02 | — | — | US | disclosed |
| US-20070072968-A1 | Metal salts of quinolinols and quinolinol derivatives as corrosion inhibitors | HENKEL AG & CO. KGAA (DE) | 2007-03-29 | — | — | US | disclosed |
| US-20070072968-A1 | Metal salts of quinolinols and quinolinol derivatives as corrosion inhibitors | HENKEL AG & CO. KGAA (DE) | 2007-03-29 | — | — | US | disclosed |
| US-20070049722-A1 | Quinolinols as fluxing and accelerating agents for underfill compositions | HENKEL AG & CO. KGAA (DE) | 2007-03-01 | — | — | US | disclosed |
| US-20070049722-A1 | Quinolinols as fluxing and accelerating agents for underfill compositions | HENKEL AG & CO. KGAA (DE) | 2007-03-01 | — | — | US | disclosed |
| US-20070049665-A1 | Quinolinols and quinolinol derivatives as adhesion promoters in die attach adhesives | HENKEL AG & CO. KGAA (DE) | 2007-03-01 | — | — | US | disclosed |
| US-20070049665-A1 | Quinolinols and quinolinol derivatives as adhesion promoters in die attach adhesives | HENKEL AG & CO. KGAA (DE) | 2007-03-01 | — | — | US | disclosed |
| EP-1758163-A1 | Quinolinols as fluxing and accelerating agents for underfill compositions | National Starch and Chemical Investment Holding Corporation (US) | 2007-02-28 | — | — | EP | disclosed |
| EP-1758164-A1 | Quinolinols and quinolinol derivatives as adhesion promoters in die attach adhesives | National Starch and Chemical Investment Holding Corporation (US) | 2007-02-28 | — | — | EP | disclosed |
| WO-2006067074-A1 | ELECTROLUMINESCENT METAL COMPLEXES WITH NUCLEOPHILIC CARBENE LIGANDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044107-A1 | Inhibitors of JMJD2C as Anticancer Agents | KDM2A, KDM1B, KDM5C | KDM4E 17/4885L3MBTL1 2157/4885TP53 269/4885 |
| US-20120196853-A1 | Novel Quinoline-Hepcidine Antagonists | HAMP, SLC40A1, FTH1 | KDM4E 3190/4885L3MBTL1 4549/4885TP53 4470/4885 |
| US-20070049722-A1 | Quinolinols as fluxing and accelerating agents for underfill compositions | TAF1L, TAF1, TAF5 | KDM4E 1292/4885L3MBTL1 3818/4885TP53 2606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.