⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL11480827 | 0.81 | PTPN1 (0.42) | — | |
| SCHEMBL6804224 | 0.75 | — | — | |
| SCHEMBL25575151 | 0.75 | DHODH (0.46) | — | |
| SCHEMBL8197514 | 0.75 | LMNA (0.50) | — | |
| SCHEMBL18105662 | 0.73 | — | — | |
| SCHEMBL7204207 | 0.73 | — | — | |
| SCHEMBL1286669 | 0.70 | HTT (0.48) | — | |
| SCHEMBL22415683 | 0.70 | MEN1 (0.37) | — | |
| SCHEMBL13898648 | 0.69 | KIF11 (0.35) | — | |
| SCHEMBL11631954 | 0.69 | ALOX15 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2246343-B1 | PROCESS FOR PRODUCTION OF THIOPHENE COMPOUND AND INTERMEDIATE THEREOF | NISSAN CHEMICAL IND LTD (JP) | 2016-05-18 | — | — | EP | disclosed |
| US-8642786-B2 | Process for producing thiophene compound and intermediate thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2014-02-04 | — | — | US | disclosed |
| US-20140005413-A2 | PROCESS FOR PRODUCING THIOPHENE COMPOUND AND INTERMEDIATE THEREOF | NISSAN CHEMICAL IND LTD (JP) | 2014-01-02 | — | — | US | disclosed |
| US-20130204013-A1 | PROCESS FOR PRODUCING THIOPHENE COMPOUND AND INTERMEDIATE THEREOF | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2013-08-08 | — | — | US | disclosed |
| US-8420849-B2 | Process for producing thiophene compound and intermediate thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2013-04-16 | — | — | US | disclosed |
| US-8399685-B2 | Process for producing thiophene compound and intermediate thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2013-03-19 | — | — | US | disclosed |
| US-20130060050-A1 | PROCESS FOR PRODUCING THIOPHENE COMPOUND AND INTERMEDIATE THEREOF | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2013-03-07 | — | — | US | disclosed |
| US-20110124884-A1 | PROCESS FOR PRODUCING THIOPHENE COMPOUND AND INTERMEDIATE THEREOF | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-05-26 | — | — | US | disclosed |
| EP-2246343-A1 | PROCESS FOR PRODUCTION OF THIOPHENE COMPOUND AND INTERMEDIATE THEREOF | Nissan Chemical Industries, Ltd. (JP) | 2010-11-03 | — | — | EP | disclosed |
| EP-1904472-A1 | THIOPHENE COMPOUNDS AND THROMBOPOIETIN RECEPTOR ACTIVATORS | Nissan Chemical Industries, Ltd. (JP) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007010954-A1 | THIOPHENE COMPOUNDS AND THROMBOPOIETIN RECEPTOR ACTIVATORS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2007-01-25 | — | — | WO | disclosed |
| US-4242518-A | Thiophene compounds and their manufacture | BASF AKTIENGESELLSCHAFT (DE) | 1980-12-30 | — | — | US | disclosed |
| US-4239897-A | Thiophene compounds and their manufacture | BASF AKTIENGESELLSCHAFT (DE) | 1980-12-16 | — | — | US | disclosed |