Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17874312 | 0.89 | KMT2A (0.47) | KMT2AMEN1HSP90AA1NPC1RAB9A | |
| SCHEMBL17330420 | 0.85 | KMT2A (0.47) | KMT2AMEN1HSP90AA1NPC1RAB9A | |
| SCHEMBL30639502 | 0.83 | KMT2A (0.47) | KMT2AMEN1HSP90AA1NPC1RAB9A | |
| SCHEMBL27032851 | 0.83 | KMT2A (0.47) | KMT2AMEN1HSP90AA1NPC1RAB9A | |
| SCHEMBL17874270 | 0.83 | LMNA (0.46) | KMT2AMEN1HSP90AA1NPC1RAB9A | |
| SCHEMBL18526459 | 0.82 | KMT2A (0.49) | KMT2AMEN1HSP90AA1NPC1RAB9A | |
| SCHEMBL18496687 | 0.81 | LMNA (0.44) | KMT2AMEN1HSP90AA1NPC1RAB9A | |
| SCHEMBL17330425 | 0.81 | TDP1 (0.51) | KMT2AMEN1HSP90AA1NPC1RAB9A | |
| SCHEMBL17874263 | 0.81 | F2 (0.47) | KMT2AMEN1HSP90AA1NPC1RAB9A | |
| SCHEMBL5372093 | 0.79 | AGTR1 (0.55) | KMT2AMEN1HSP90AA1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016102493-A1 | IMIDAZOPYRIDINE EZH2 INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-06-30 | — | — | WO | disclosed |
| WO-2016102493-A1 | IMIDAZOPYRIDINE EZH2 INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-06-30 | — | — | WO | disclosed |