Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17874312 | 0.86 | KMT2A (0.47) | ADORA3KMT2AMEN1HSP90AA1NPC1 | |
| SCHEMBL17887400 | 0.83 | F2 (0.38) | F2ADORA3LMNAMAPTALDH1A1 | |
| SCHEMBL17330420 | 0.83 | KMT2A (0.47) | F2ADORA3KMT2AMEN1HSP90AA1 | |
| SCHEMBL27032851 | 0.81 | KMT2A (0.47) | F2KMT2AMEN1HSP90AA1NPC1 | |
| SCHEMBL30639502 | 0.81 | KMT2A (0.47) | F2KMT2AMEN1HSP90AA1NPC1 | |
| SCHEMBL17874239 | 0.81 | KMT2A (0.43) | ADORA3KMT2AMEN1HSP90AA1NPC1 | |
| SCHEMBL17874256 | 0.80 | C5AR1 (0.42) | C5AR1ADAM17SMN1; SMN2RBP4TTR | |
| SCHEMBL17874270 | 0.80 | LMNA (0.46) | ADORA3KMT2AMEN1HSP90AA1NPC1 | |
| SCHEMBL17874252 | 0.80 | C5AR1 (0.41) | LMNAC5AR1ADAM17SMN1; SMN2RBP4 | |
| SCHEMBL18526459 | 0.79 | KMT2A (0.49) | ADORA3KMT2AMEN1HSP90AA1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016102493-A1 | IMIDAZOPYRIDINE EZH2 INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-06-30 | — | — | WO | disclosed |
| WO-2016102493-A1 | IMIDAZOPYRIDINE EZH2 INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-06-30 | — | — | WO | disclosed |