Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | RBP4 | P02753 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | ATP4A | P20648 | 1/20 | 0.35 |
| ▸ | ATP4B | P51164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17874321 | 0.84 | C5AR1 (0.39) | C5AR1L3MBTL1HTR2CSLC6A4HTR2A | |
| SCHEMBL17887387 | 0.84 | FFAR2 (0.38) | C5AR1L3MBTL1HTR2CSLC6A4HTR2A | |
| SCHEMBL17874252 | 0.84 | C5AR1 (0.41) | C5AR1L3MBTL1HTR2CSLC6A4HTR2A | |
| SCHEMBL17874266 | 0.82 | AOC3 (0.44) | L3MBTL1STAT3HTTSMN1; SMN2ATP4A | |
| SCHEMBL31026204 | 0.81 | L3MBTL1 (0.44) | L3MBTL1STAT3HTTSMN1; SMN2ATP4A | |
| SCHEMBL17330449 | 0.81 | L3MBTL1 (0.44) | L3MBTL1STAT3HTTSMN1; SMN2ATP4A | |
| SCHEMBL17887407 | 0.81 | PTGS1 (0.36) | MCHR1 | |
| SCHEMBL17874263 | 0.80 | F2 (0.47) | C5AR1ADAM17RBP4TTRSMN1; SMN2 | |
| SCHEMBL17874273 | 0.78 | L3MBTL1 (0.40) | L3MBTL1STAT3HTTSMN1; SMN2SQOR | |
| SCHEMBL17874232 | 0.78 | MEN1 (0.44) | L3MBTL1STAT3HTTSMN1; SMN2ATP4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016102493-A1 | IMIDAZOPYRIDINE EZH2 INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-06-30 | — | — | WO | disclosed |
| WO-2016102493-A1 | IMIDAZOPYRIDINE EZH2 INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-06-30 | — | — | WO | disclosed |