Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21437805 | 0.81 | L3MBTL1 (0.54) | L3MBTL1ALDH1A1MAPTKDM4CNPC1 | |
| SCHEMBL6888866 | 0.81 | L3MBTL1 (0.54) | L3MBTL1ALDH1A1MAPTKDM4CNPC1 | |
| SCHEMBL27911792 | 0.81 | ALDH1A1 (0.63) | L3MBTL1ALDH1A1MAPTKDM4CNPC1 | |
| SCHEMBL2537598 | 0.81 | L3MBTL1 (0.54) | L3MBTL1ALDH1A1MAPTKDM4CNPC1 | |
| SCHEMBL12019619 | 0.81 | ALDH1A1 (0.54) | L3MBTL1ALDH1A1MAPTKDM4CNPC1 | |
| Bromide SCHEMBL6170902 | 0.80 | ALDH1A1 (0.53) | L3MBTL1ALDH1A1MAPTKDM4CNPC1 | |
| SCHEMBL27715023 | 0.78 | ALDH1A1 (0.58) | L3MBTL1ALDH1A1MAPTKDM4CNPC1 | |
| SCHEMBL6887957 | 0.78 | ALDH1A1 (0.46) | L3MBTL1ALDH1A1MAPTKDM4CNPC1 | |
| SCHEMBL20746280 | 0.77 | ALDH1A1 (0.54) | L3MBTL1ALDH1A1MAPTKDM4CNPC1 | |
| SCHEMBL6889314 | 0.77 | ALDH1A1 (0.54) | L3MBTL1ALDH1A1MAPTKDM4CNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2483268-B1 | PYRIDINYL-IMIDAZOLONE DERIVATIVES FOR INHIBITING PI3 KINASES | MERCK PATENT GMBH (DE) | 2016-06-29 | — | — | EP | disclosed |