Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL27797533 | 0.95 | ALDH1A1 (0.32) | ALDH1A1MAPK1TDP1CYP2A6 | |
| Benzene SCHEMBL27466978 | 0.95 | ALDH1A1 (0.35) | ALDH1A1MAPK1TDP1CYP2A6TP53 | |
| Benzene SCHEMBL2295857 | 0.95 | — | — | |
| Benzene SCHEMBL27723606 | 0.95 | ALDH1A1 (0.35) | ALDH1A1MAPK1TDP1CYP2A6TP53 | |
| Benzene SCHEMBL30314930 | 0.95 | ALDH1A1 (0.35) | ALDH1A1MAPK1TDP1CYP2A6TP53 | |
| Benzene SCHEMBL10970429 | 0.90 | ALDH1A1 (0.33) | ALDH1A1MAPK1TDP1CYP2A6TP53 | |
| Benzene SCHEMBL28784982 | 0.90 | ALDH1A1 (0.33) | ALDH1A1MAPK1TDP1CYP2A6TP53 | |
| Benzene SCHEMBL27731871 | 0.90 | ALDH1A1 (0.33) | ALDH1A1MAPK1TDP1CYP2A6TP53 | |
| Benzene SCHEMBL29287815 | 0.90 | ALDH1A1 (0.33) | ALDH1A1MAPK1TDP1CYP2A6TP53 | |
| Benzene SCHEMBL28843807 | 0.90 | ALDH1A1 (0.33) | ALDH1A1MAPK1TDP1CYP2A6TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106117682-A | A kind of rubber packing material and preparation method thereof | 安徽嘉木橡塑工业有限公司 | 2016-11-16 | — | — | CN | claimed |
| CN-103992828-B | There is lubricated wear-resistant diesel oil starting protection additive | QUANZHOU CITY OUMEI LUBRICANT PRODUCTS CO., LTD. (CN) | 2016-05-18 | — | — | CN | claimed |
| US-20210380548-A1 | Fused [1,2,4]Thiadiazine Derivatives Which Act as KAT Inhibitors of the MYST Family | CTXT PTY LIMITED (AU) | 2021-12-09 | — | — | US | disclosed |
| WO-2021030556-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2021-02-18 | — | — | WO | disclosed |
| US-10458995-B2 | Combinatorial synthesis and biomarker development | TEN30 BIOSCIENCES, INC. | 2019-10-29 | — | — | US | disclosed |
| US-20190113521-A1 | COMBINATORIAL SYNTHESIS AND BIOMARKER DEVELOPMENT | TEN30 BIOSCIENCES, INC. | 2019-04-18 | — | — | US | disclosed |
| WO-2019043139-A1 | FUSED [1,2,4]THIADIAZINE DERIVATIVES WHICH ACT AS KAT INHIBITORS OF THE MYST FAMILY | CTXT PTY LIMITED (AU) | 2019-03-07 | — | — | WO | disclosed |
| CN-109423267-A | A kind of vapour phase inhibitor and preparation method thereof | 中国石油化工股份有限公司 | 2019-03-05 | — | — | CN | disclosed |
| US-20190031599-A1 | INDANE DERIVATIVES AS MGLUR7 MODULATORS | TAKEDA CAMBRIDGE LIMITED (GB) | 2019-01-31 | — | — | US | disclosed |
| US-10041182-B2 | Reaction products of amino acids and epoxies | ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) | 2018-08-07 | — | — | US | disclosed |
| EP-3040451-B1 | REACTION PRODUCTS OF AMINO ACIDS AND EPOXIES | ROHM & HAAS ELECT MAT (US) | 2018-07-25 | — | — | EP | disclosed |
| US-20100069374-A1 | Tricyclic benzopyrane compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-03-18 | — | — | US | disclosed |
| US-20100069374-A1 | Tricyclic benzopyrane compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-03-18 | — | — | US | disclosed |
| US-7652008-B2 | 2,2,7,9-tetramethyl-4-[(2-phenylethyl)amino]-3,4-dihydro-2H-pyrano[2,3-g]quinolin-3-ol; 3-hydroxy-2,2,9-trimethyl-4-[(2-phenylethyl)amino]-3,4-dihydro-2H-pyrano[2,3-g]quinolin-7-carbonitrile; have the prolongation effect on refractory period | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-01-26 | — | — | US | disclosed |
| US-7652008-B2 | 2,2,7,9-tetramethyl-4-[(2-phenylethyl)amino]-3,4-dihydro-2H-pyrano[2,3-g]quinolin-3-ol; 3-hydroxy-2,2,9-trimethyl-4-[(2-phenylethyl)amino]-3,4-dihydro-2H-pyrano[2,3-g]quinolin-7-carbonitrile; have the prolongation effect on refractory period | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-01-26 | — | — | US | disclosed |
| US-20090088588-A1 | Organocatalysts and methods of use in chemical synthesis | REGENTS OF THE UNIVERSITY OF NEW MEXICO | 2009-04-02 | — | — | US | disclosed |
| CN-100384877-C | Antibody ('11c7') anti nogo a and its pharmaceutical use | NOVATIS AG (CH) | 2008-04-30 | — | — | CN | disclosed |
| US-20080004262-A1 | Tricyclic Benzopyrane Compound as Anti-Arrhythmic Agents | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2008-01-03 | — | — | US | disclosed |
| US-20080004262-A1 | Tricyclic Benzopyrane Compound as Anti-Arrhythmic Agents | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2008-01-03 | — | — | US | disclosed |
| CN-1747971-A | Antibody ('11c7') anti nogo a and its pharmaceutical use | NOVATIS AG (CH) | 2006-03-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069374-A1 | Tricyclic benzopyrane compound | CBR1, CBR3, CYP2C9 | ALDH1A1 2252/4885MAPK1 3196/4885TDP1 4038/4885 |
| US-20210380548-A1 | Fused [1,2,4]Thiadiazine Derivatives Which Act as KAT Inhibitors of the MYST Family | KAT5, KAT6A, KAT2A | ALDH1A1 2920/4885MAPK1 1076/4885TDP1 925/4885 |
| US-10041182-B2 | Reaction products of amino acids and epoxies | EPOR, DAO, ETF1 | ALDH1A1 523/4885MAPK1 1900/4885TDP1 1132/4885 |
| US-20190031599-A1 | INDANE DERIVATIVES AS MGLUR7 MODULATORS | GRM7, GRIN2B, GRM1 | ALDH1A1 2821/4885MAPK1 1994/4885TDP1 3784/4885 |
| US-20190113521-A1 | COMBINATORIAL SYNTHESIS AND BIOMARKER DEVELOPMENT | APP, PSEN2, PSEN1 | ALDH1A1 4306/4885MAPK1 4446/4885TDP1 3289/4885 |
| US-20080004262-A1 | Tricyclic Benzopyrane Compound as Anti-Arrhythmic Agents | CBR1, CBR3, SCN8A | ALDH1A1 2087/4885MAPK1 2627/4885TDP1 3969/4885 |
| US-10458995-B2 | Combinatorial synthesis and biomarker development | APP, PSEN2, PSEN1 | ALDH1A1 4308/4885MAPK1 4438/4885TDP1 3300/4885 |
| US-20090088588-A1 | Organocatalysts and methods of use in chemical synthesis | ICMT, PPOX, CYP4F3 | ALDH1A1 1418/4885MAPK1 4756/4885TDP1 3853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.