SCHEMBL17876182

SCHEMBL17876182

CC1(C)Oc2ccc(-c3cccc4c3oc3ccccc34)cc2-c2cc(-n3c4ccccc4c4ccccc43)ccc2O1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.46
PRKDC P78527 5/20 0.38
GGPS1 O95749 1/20 0.36
PTGES2 Q9H7Z7 1/20 0.34
PRMT5 O14744 1/20 0.34
WDR77 Q9BQA1 1/20 0.34
MEN1 O00255 1/20 0.34
CYP2C19 P33261 1/20 0.34
KMT2A Q03164 1/20 0.34
EDNRB P24530 1/20 0.33
EDNRA P25101 1/20 0.33
AVPR1A P37288 1/20 0.33
ATM Q13315 2/20 0.32
HDAC8 Q9BY41 1/20 0.32
RXFP1 Q9HBX9 3/20 0.31
ALDH1A1 P00352 2/20 0.31
LMNA P02545 2/20 0.31
PPARG P37231 2/20 0.31
NR2E3 Q9Y5X4 2/20 0.31
NCOR2 Q9Y618 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17876124 0.95 ALOX5 (0.44) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL17877863 0.90 ALOX5 (0.39) ALOX5PRKDCGGPS1AVPR1A
SCHEMBL17876187 0.89 ALOX5 (0.34) ALOX5EDNRBEDNRAATMKDM4E
SCHEMBL17876188 0.88 ALOX5 (0.58) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL17876082 0.86 ALOX5 (0.47) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL17877867 0.86 ALOX5 (0.37) ALOX5PRKDCGGPS1EDNRBEDNRA
SCHEMBL17877701 0.86 ALOX5 (0.37) ALOX5PRKDCGGPS1EDNRBEDNRA
SCHEMBL17876184 0.86 AHR (0.34) PRKDCMEN1KMT2AEDNRBEDNRA
SCHEMBL17876181 0.86 HSP90AA1 (0.34) MEN1CYP2C19KMT2AEDNRBEDNRA
SCHEMBL18252548 0.85 ALOX5 (0.53) ALOX5PRKDCGGPS1PTGES2PRMT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-03-03 US disclosed
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CRY2, CCNE2 ALOX5 3059/4885PRKDC 4858/4885GGPS1 1622/4885
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 ALOX5 3059/4885PRKDC 4858/4885GGPS1 1622/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.