Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 8/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12296317 | 0.91 | CYP2C9 (0.66) | CYP2C9CYP2C19CYP3A4KDM4EPKM | |
| SCHEMBL16447496 | 0.90 | CYP2C9 (0.78) | CYP2C9CYP2C19CYP3A4KDM4EPKM | |
| SCHEMBL17876467 | 0.87 | CYP2C9 (0.81) | CYP2C9CYP2C19CYP3A4KDM4EPKM | |
| SCHEMBL17876754 | 0.86 | CYP2C9 (0.62) | CYP2C9CYP2C19CYP3A4KDM4EPKM | |
| SCHEMBL17876756 | 0.86 | KDM4E (0.67) | CYP2C9CYP2C19CYP3A4KDM4EPKM | |
| SCHEMBL12295435 | 0.85 | CYP2C9 (0.68) | CYP2C9CYP2C19CYP3A4KDM4EPKM | |
| SCHEMBL12295420 | 0.85 | CYP2C9 (0.73) | CYP2C9CYP2C19CYP3A4KDM4EPKM | |
| SCHEMBL13738536 | 0.83 | CYP2C9 (0.60) | CYP2C9CYP2C19CYP3A4KDM4EPKM | |
| SCHEMBL14770381 | 0.83 | CYP2C9 (0.66) | CYP2C9CYP2C19CYP3A4KDM4EPKM | |
| SCHEMBL13837938 | 0.83 | CYP2C9 (0.66) | CYP2C9CYP2C19CYP3A4KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160185774-A1 | Anti-Infective Compounds | INSTITUT PASTEUR KOREA (KR) | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185774-A1 | Anti-Infective Compounds | RABGGTB, ELANE, SERPINB1 | CYP2C9 4235/4885CYP2C19 4181/4885CYP3A4 2915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.