SCHEMBL17877394

SCHEMBL17877394

CC1(C)CC(C2CCC(CCc3cc(C(C)(C)C)c(O)c(C(C)(C)C)c3)CC2)CC(C)(C)N1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.39
GAA P10253 6/20 0.39
KDM4E B2RXH2 4/20 0.39
KMT2A Q03164 4/20 0.36
TSHR P16473 4/20 0.36
MEN1 O00255 3/20 0.36
LMNA P02545 3/20 0.36
MAOB P27338 2/20 0.36
MAOA P21397 1/20 0.36
ACHE P22303 1/20 0.36
NPSR1 Q6W5P4 3/20 0.35
CYP1A2 P05177 2/20 0.35
CYP3A4 P08684 2/20 0.35
MAPK1 P28482 2/20 0.35
BLM P54132 2/20 0.35
ATM Q13315 2/20 0.35
HIF1A Q16665 2/20 0.35
GMNN O75496 1/20 0.35
GABBR2 O75899 1/20 0.35
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17877396 1.00 ALDH1A1 (0.39) ALDH1A1GAAKDM4EKMT2ATSHR
SCHEMBL17877397 0.90 MEN1 (0.33) ALDH1A1GAAKDM4EKMT2ATSHR
SCHEMBL18539827 0.89
SCHEMBL20000741 0.88 ALDH1A1 (0.41) ALDH1A1GAAKDM4EKMT2ATSHR
SCHEMBL17877411 0.85 POLB (0.32) KMT2AMEN1POLB
SCHEMBL17877398 0.85 KMT2A (0.34) ALDH1A1GAAKDM4EKMT2ATSHR
SCHEMBL19677860 0.82 ALDH1A1 (0.51) ALDH1A1GAAKDM4EKMT2ATSHR
SCHEMBL17881252 0.82 CA1 (0.36) ALDH1A1GAAKDM4EALOX15MAPT
SCHEMBL17877414 0.81 GAA (0.45) ALDH1A1GAAKDM4EKMT2ATSHR
SCHEMBL17877399 0.81 HMGCR (0.38) ALDH1A1GAAKDM4EKMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10018875-B2 Curved liquid crystal display and method of manufacturing the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-07-10 US disclosed
US-10018875-B2 Curved liquid crystal display and method of manufacturing the same SAMSUNG DISPLAY CO., LTD. (KR) 2018-07-10 US disclosed
US-20180086981-A1 LIQUID CRYSTAL COMPOSITION AND DISPLAY DEVICE INCLUDING THE SAME TCL CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2018-03-29 US disclosed
US-20170052412-A1 CURVED LIQUID CRYSTAL DISPLAY AND METHOD OF MANUFACTURING THE SAME TCL CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2017-02-23 US disclosed
US-20170052412-A1 CURVED LIQUID CRYSTAL DISPLAY AND METHOD OF MANUFACTURING THE SAME TCL CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2017-02-23 US disclosed
US-20170038642-A1 ALIGNMENT LAYER AND LIQUID CRYSTAL DISPLAY INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-02-09 US disclosed
US-20170038642-A1 ALIGNMENT LAYER AND LIQUID CRYSTAL DISPLAY INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-02-09 US disclosed
US-20160185763-A1 LIQUID CRYSTAL STABILIZER, LIQUID CRYSTAL COMPOSITION INCLUDING THE SAME, AND LIQUID CRYSTAL DISPLAY INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-30 US disclosed
US-20160185763-A1 LIQUID CRYSTAL STABILIZER, LIQUID CRYSTAL COMPOSITION INCLUDING THE SAME, AND LIQUID CRYSTAL DISPLAY INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180086981-A1 LIQUID CRYSTAL COMPOSITION AND DISPLAY DEVICE INCLUDING THE SAME CNOT1, CXCR1, CCRL2 ALDH1A1 309/4885GAA 4709/4885KDM4E 1824/4885
US-20160185763-A1 LIQUID CRYSTAL STABILIZER, LIQUID CRYSTAL COMPOSITION INCLUDING THE SAME, AND LIQUID CRYSTAL DISPLAY INCLUDING THE SAME PYM1, YBX3, MLX ALDH1A1 2589/4885GAA 4819/4885KDM4E 1512/4885
US-10018875-B2 Curved liquid crystal display and method of manufacturing the same PDCD2L, VCL, LAS1L ALDH1A1 2364/4885GAA 2818/4885KDM4E 3436/4885
US-20170052412-A1 CURVED LIQUID CRYSTAL DISPLAY AND METHOD OF MANUFACTURING THE SAME PDCD2L, VCL, LAS1L ALDH1A1 2364/4885GAA 2818/4885KDM4E 3436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.