SCHEMBL17877607

SCHEMBL17877607

CCOc1c(F)c(F)c(S(=O)(=O)NS(=O)(=O)C(F)(F)F)c(F)c1F

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.37
CA2 P00918 3/20 0.37
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
MMP8 P22894 1/20 0.32
MMP13 P45452 1/20 0.32
EPHX1 P07099 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17881657 0.88 CA1 (0.35) CA1CA2MMP1MMP2MMP9
SCHEMBL20415032 0.85 CA1 (0.35) CA1CA2MMP1MMP2MMP9
SCHEMBL12129751 0.79 CA1 (0.56) CA1CA2MMP1MMP2MMP9
SCHEMBL12640563 0.77 CA1 (0.32) CA1CA2
SCHEMBL20439590 0.76 CA1 (0.44) CA1CA2MMP1MMP2MMP9
SCHEMBL29899458 0.73 CA1 (0.37) CA1CA2MMP1MMP2MMP9
SCHEMBL22484603 0.73 CA1 (0.48) CA1CA2MMP1MMP2MMP9
SCHEMBL20415014 0.73 CA1 (0.44) CA1CA2MMP1MMP2MMP9
SCHEMBL16683131 0.73 ALDH1A1 (0.40) CA1CA2ALDH1A1MAPT
SCHEMBL23964412 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9605154-B2 Curable coloring composition, cured film, color filter, method for manufacturing color filter, solid-state image pickup element, picture display device, and triarylmethane compound FUJIFILM CORPORATION (JP) 2017-03-28 US disclosed
US-9605154-B2 Curable coloring composition, cured film, color filter, method for manufacturing color filter, solid-state image pickup element, picture display device, and triarylmethane compound FUJIFILM CORPORATION (JP) 2017-03-28 US disclosed
US-20160185969-A1 CURABLE COLORING COMPOSITION, CURED FILM, COLOR FILTER, METHOD FOR MANUFACTURING COLOR FILTER, SOLID-STATE IMAGE PICKUP ELEMENT, PICTURE DISPLAY DEVICE, AND TRIARYLMETHANE COMPOUND FUJIFILM CORPORATION (JP) 2016-06-30 US disclosed
US-20160185969-A1 CURABLE COLORING COMPOSITION, CURED FILM, COLOR FILTER, METHOD FOR MANUFACTURING COLOR FILTER, SOLID-STATE IMAGE PICKUP ELEMENT, PICTURE DISPLAY DEVICE, AND TRIARYLMETHANE COMPOUND FUJIFILM CORPORATION (JP) 2016-06-30 US disclosed