SCHEMBL20439590

SCHEMBL20439590

Cc1c(F)c(F)c(S(=O)(=O)NS(=O)(=O)C(F)(F)F)c(F)c1F

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.44
CA2 P00918 4/20 0.44
MMP1 P03956 1/20 0.38
MMP2 P08253 1/20 0.38
MMP9 P14780 1/20 0.38
MMP8 P22894 1/20 0.38
MMP13 P45452 1/20 0.38
F2 P00734 1/20 0.32
PRSS1 P07477 1/20 0.32
PRSS2 P07478 1/20 0.32
PRSS3 P35030 1/20 0.32
PTPN11 Q06124 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12129751 0.88 CA1 (0.56) CA1CA2MMP1MMP2MMP9
SCHEMBL25737830 0.81 CA1 (0.58) CA1CA2MMP1MMP2MMP9
SCHEMBL20415014 0.81 CA1 (0.44) CA1CA2MMP1MMP2MMP9
SCHEMBL22484603 0.81 CA1 (0.48) CA1CA2MMP1MMP2MMP9
SCHEMBL20415032 0.77 CA1 (0.35) CA1CA2MMP1MMP2MMP9
SCHEMBL25117857 0.77 CA1 (0.39) CA1CA2MMP1MMP2MMP9
SCHEMBL22484906 0.76 CA1 (0.37) CA1CA2MMP1MMP2MMP9
SCHEMBL17877607 0.76 CA1 (0.37) CA1CA2MMP1MMP2MMP9
SCHEMBL13588295 0.76 CA1 (0.52) CA1CA2MMP1MMP2MMP9
SCHEMBL17881657 0.74 CA1 (0.35) CA1CA2MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11204552-B2 Radiation-sensitive composition, pattern-forming method and radiation-sensitive acid generating agent JSR CORPORATION (JP) 2021-12-21 US disclosed
US-20200041902-A9 RADIATION-SENSITIVE COMPOSITION, PATTERN-FORMING METHOD AND RADIATION-SENSITIVE ACID GENERATING AGENT JSR CORPORATION (JP) 2020-02-06 US disclosed
US-20180217497-A1 PATTERN FORMING METHOD AND ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2018-08-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11204552-B2 Radiation-sensitive composition, pattern-forming method and radiation-sensitive acid generating agent NOS1, ADCY1, IFNAR1 CA1 54/4885CA2 141/4885MMP1 3875/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.