SCHEMBL17877643

SCHEMBL17877643

N#Cc1ccc2c(c1)c1ccccc1n2-c1ccc2c(c1)-c1cc(-c3cccc4c3oc3ccccc34)ccc1CSC2

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.39
PRKDC P78527 4/20 0.35
PRMT5 O14744 1/20 0.33
WDR77 Q9BQA1 1/20 0.33
TNKS O95271 1/20 0.32
GGPS1 O95749 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17877793 0.97 ALOX5 (0.37) ALOX5PRKDCPRMT5WDR77TNKS
SCHEMBL17877804 0.97 ALOX5 (0.37) ALOX5PRKDCPRMT5WDR77TNKS
SCHEMBL17877728 0.91 ALOX5 (0.40) ALOX5PRKDCPRMT5WDR77TNKS
SCHEMBL17877644 0.90 TNKS (0.32) TNKS
SCHEMBL17875771 0.90 ALOX5 (0.46) ALOX5PRKDCPRMT5WDR77GGPS1
SCHEMBL17877646 0.89 TNKS (0.33) TNKS
SCHEMBL17877648 0.89 TNKS (0.33) TNKS
SCHEMBL17877806 0.88 ALOX5 (0.37) ALOX5PRKDCPRMT5WDR77TNKS
SCHEMBL17877715 0.88 ALOX5 (0.37) ALOX5PRKDCPRMT5WDR77TNKS
SCHEMBL17877825 0.87 TNKS (0.31) TNKS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-03-03 US disclosed
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CRY2, CCNE2 ALOX5 3059/4885PRKDC 4858/4885PRMT5 3745/4885
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 ALOX5 3059/4885PRKDC 4858/4885PRMT5 3745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.