SCHEMBL17877703

SCHEMBL17877703

CC1(C)Oc2ccc(-n3c4ccccc4c4ccccc43)cc2-c2cc(-n3c4ccccc4c4cc(C#N)ccc43)ccc2O1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ABCC9 O60706 5/20 0.36
KDM1A O60341 1/20 0.36
PTGER4 P35408 1/20 0.34
RORC P51449 4/20 0.34
ABCB1 P08183 3/20 0.34
TDP2 O95551 1/20 0.33
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
CASP1 P29466 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
USP14 P54578 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17877829 1.00 ABCC9 (0.36) ABCC9KDM1APTGER4RORCABCB1
SCHEMBL17877838 1.00 ABCC9 (0.36) ABCC9KDM1APTGER4RORCABCB1
SCHEMBL17877834 1.00 ABCC9 (0.36) ABCC9KDM1APTGER4RORCABCB1
SCHEMBL17877869 0.96 ABCC9 (0.34) ABCC9KDM1APTGER4RORCABCB1
SCHEMBL17877871 0.96 ABCC9 (0.34) ABCC9KDM1APTGER4RORCABCB1
SCHEMBL17877835 0.94 KDM1A (0.36) ABCC9KDM1AABCB1TDP2USP14
SCHEMBL17877831 0.91 ABCC9 (0.33) ABCC9KDM1APTGER4ABCB1
SCHEMBL17877860 0.88 ABCC9 (0.34) ABCC9KDM1APTGER4
SCHEMBL17877861 0.88 ABCC9 (0.34) ABCC9KDM1APTGER4
SCHEMBL17877896 0.88 EDNRA (0.33) ABCC9KDM1APTGER4ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-03-03 US disclosed
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CRY2, CCNE2 ABCC9 2641/4885KDM1A 1206/4885PTGER4 1275/4885
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 ABCC9 2641/4885KDM1A 1206/4885PTGER4 1275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.