SCHEMBL17879148

SCHEMBL17879148

c1ccc2c(c1)Oc1ccccc1N2c1ccc(-c2cnc3nccnc3n2)cc1

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ADK P55263 2/20 0.34
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
BCHE P06276 1/20 0.31
ATR Q13535 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17851113 0.86 NPC1 (0.33) ADKNPC1RAB9ASMN1; SMN2BCHE
SCHEMBL17879145 0.86 BCHE (0.45) ADKNPC1RAB9ASMN1; SMN2BCHE
SCHEMBL18748048 0.83 MEN1 (0.34) RAB9A
SCHEMBL17851116 0.82 HDAC6 (0.40) ADKNPC1RAB9ASMN1; SMN2BCHE
SCHEMBL17851055 0.81 NPC1 (0.51) NPC1RAB9ASMN1; SMN2BCHE
SCHEMBL13308158 0.77 EGLN1 (0.40) NPC1RAB9A
SCHEMBL20496063 0.77 MAPT (0.47) SMN1; SMN2ATR
SCHEMBL23172554 0.75 NPC1 (0.35) NPC1RAB9ASMN1; SMN2
SCHEMBL17952726 0.75 PIM1 (0.36)
SCHEMBL17278542 0.75 RAB9A (0.50) NPC1RAB9ASMN1; SMN2BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10862047-B2 Organic electroluminescent device KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2020-12-08 US disclosed
US-10658596-B2 2020-05-19 US disclosed
US-10256415-B2 Light-emitting material, organic light-emitting device, and compound KYULUX, INC. (JP) 2019-04-09 US disclosed
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND KYULUX, INC. (JP) 2017-07-27 US disclosed
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND KYULUX, INC. (JP) 2017-07-27 US disclosed
US-20170163010-A1 ORGANIC LIGHT-EMITTING ELEMENT KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2017-06-08 US disclosed
US-20170163010-A1 ORGANIC LIGHT-EMITTING ELEMENT KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2017-06-08 US disclosed
US-20170110670-A1 LIGHT-EMITTING MATERIAL, ORGANIC LIGHT-EMITTING DEVICE, AND COMPOUND KYULUX, INC. (JP) 2017-04-20 US disclosed
US-20170110670-A1 LIGHT-EMITTING MATERIAL, ORGANIC LIGHT-EMITTING DEVICE, AND COMPOUND KYULUX, INC. (JP) 2017-04-20 US disclosed
US-20160190478-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-06-30 US disclosed
US-20160190478-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170110670-A1 LIGHT-EMITTING MATERIAL, ORGANIC LIGHT-EMITTING DEVICE, AND COMPOUND H1-0, CRY1, CRY2 ADK 4633/4885NPC1 3760/4885RAB9A 1293/4885
US-10256415-B2 Light-emitting material, organic light-emitting device, and compound H1-0, CRY1, CRY2 ADK 4633/4885NPC1 3760/4885RAB9A 1293/4885
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND CRY1, CRY2, CYBA ADK 4472/4885NPC1 3146/4885RAB9A 4082/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.