Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.60 |
| ▸ | CTSK | P43235 | 3/20 | 0.60 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17884306 | 0.95 | CTSS (0.66) | CTSSCTSKCA2PSENENKDM4E | |
| SCHEMBL17884325 | 0.85 | CTSS (0.63) | CTSSCTSKCA2PSENENKDM4E | |
| SCHEMBL17880434 | 0.84 | CTSK (0.58) | CTSSCTSKCA2PSENEN | |
| SCHEMBL13921008 | 0.83 | CTSS (0.67) | CTSSCTSKCA2PSENENKDM4E | |
| SCHEMBL13921024 | 0.83 | CTSS (0.67) | CTSSCTSKCA2PSENENKDM4E | |
| SCHEMBL17884331 | 0.83 | CTSK (0.63) | CTSSCTSKCA2CAPN1 | |
| SCHEMBL28969873 | 0.82 | CTSS (0.69) | CTSSCTSKCA2PSENENKDM4E | |
| SCHEMBL17880437 | 0.81 | CTSK (0.49) | CTSSCTSKCA2CAPN1 | |
| SCHEMBL13934344 | 0.81 | CTSK (0.67) | CTSSCTSKCA2PSENENCAPN1 | |
| SCHEMBL13934284 | 0.81 | CTSK (0.67) | CTSSCTSKCA2PSENENCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160185821-A1 | Z-SELECTIVE OLEFIN METATHESIS OF PEPTIDES | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185821-A1 | Z-SELECTIVE OLEFIN METATHESIS OF PEPTIDES | QPCT, PTMS, MAX | CTSS 203/4885CTSK 194/4885CA2 3535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.