Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 6/20 | 0.37 |
| ▸ | TFPI | P10646 | 6/20 | 0.35 |
| ▸ | PTH1R | Q03431 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | GLP1R | P43220 | 1/20 | 0.31 |
| ▸ | SCTR | P47872 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17880420 | 0.97 | KEAP1 (0.35) | KEAP1TFPIPTH1RRXFP1GLP1R | |
| SCHEMBL17880425 | 0.69 | MMP2 (0.38) | GLP1R | |
| SCHEMBL8062301 | 0.66 | KEAP1 (0.45) | KEAP1TFPIRXFP1 | |
| SCHEMBL8062296 | 0.66 | KEAP1 (0.45) | KEAP1TFPIRXFP1 | |
| SCHEMBL6035213 | 0.65 | TFPI (0.59) | TFPIRXFP1 | |
| SCHEMBL22640925 | 0.65 | NPY4R (0.47) | KEAP1TFPI | |
| SCHEMBL29637250 | 0.64 | KEAP1 (0.45) | KEAP1 | |
| SCHEMBL17931640 | 0.64 | NPY4R (0.45) | — | |
| SCHEMBL24336208 | 0.64 | NPY4R (0.46) | KEAP1TFPIRXFP1 | |
| SCHEMBL31437186 | 0.64 | NOD1 (0.47) | KEAP1TFPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160185821-A1 | Z-SELECTIVE OLEFIN METATHESIS OF PEPTIDES | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185821-A1 | Z-SELECTIVE OLEFIN METATHESIS OF PEPTIDES | QPCT, PTMS, MAX | KEAP1 1233/4885TFPI 2376/4885PTH1R 1066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.