Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1578986 | 0.85 | FUCA1 (0.41) | FUCA1TOP2A | |
| SCHEMBL12573463 | 0.85 | FUCA1 (0.41) | FUCA1TOP2A | |
| SCHEMBL14255133 | 0.81 | DUT (0.31) | — | |
| SCHEMBL20225134 | 0.81 | DUT (0.31) | — | |
| SCHEMBL9091553 | 0.77 | MAPT (0.33) | FUCA1 | |
| SCHEMBL16155804 | 0.76 | GBA1 (0.33) | — | |
| SCHEMBL24420699 | 0.75 | DUT (0.33) | TOP2A | |
| SCHEMBL22639340 | 0.75 | DUT (0.33) | TOP2A | |
| SCHEMBL22639184 | 0.75 | DUT (0.33) | TOP2A | |
| SCHEMBL14255134 | 0.75 | DUT (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160184336-A1 | ESTERS OF 2-DEOXY-MONOSACHARIDES WITH ANTI PROLIFERATIVE ACTIVITY | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160184336-A1 | ESTERS OF 2-DEOXY-MONOSACHARIDES WITH ANTI PROLIFERATIVE ACTIVITY | DERA, G6PD, HK2 | FUCA1 166/4885TOP2A 356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.