SCHEMBL17880694

SCHEMBL17880694

Oc1cc(Br)ccc1-c1nc2ccccc2o1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM6B O15054 1/20 0.61
KDM6A O15550 1/20 0.61
MAPT P10636 9/20 0.60
KDM4E B2RXH2 7/20 0.60
MEN1 O00255 4/20 0.60
KMT2A Q03164 4/20 0.60
TSHR P16473 2/20 0.60
TOP2A P11388 1/20 0.58
THRB P10828 2/20 0.56
ESR1 P03372 3/20 0.54
ESR2 Q92731 3/20 0.54
PTGS2 P35354 1/20 0.53
ALDH1A1 P00352 5/20 0.50
HPGD P15428 5/20 0.50
HSD17B10 Q99714 4/20 0.50
NPC1 O15118 3/20 0.50
RAB9A P51151 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
USP2 O75604 2/20 0.50
TP53 P04637 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1523547 0.89 KDM6B (0.78) KDM6BKDM6AMAPTKDM4EMEN1
SCHEMBL18875231 0.87 MAPT (0.63) KDM6BKDM6AMAPTKDM4EMEN1
SCHEMBL17654013 0.84 KDM6B (0.79) KDM6BKDM6AMAPTKDM4EMEN1
SCHEMBL30900831 0.84 KDM6B (0.79) KDM6BKDM6AMAPTKDM4EMEN1
SCHEMBL1550348 0.83 TOP2A (0.79) KDM6BKDM6AMAPTKDM4EMEN1
SCHEMBL1296601 0.83 KDM6B (0.78) KDM6BKDM6AMAPTKDM4EMEN1
SCHEMBL5307394 0.83 MAPT (0.59) KDM6BKDM6AMAPTKDM4EMEN1
SCHEMBL3317791 0.83 KDM6B (0.63) KDM6BKDM6AMAPTKDM4EMEN1
SCHEMBL10415479 0.83 MAPT (0.62) KDM6BKDM6AMAPTKDM4EMEN1
SCHEMBL29401377 0.82 TOP2A (0.82) KDM6BKDM6AMAPTKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329100-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-10-12 US disclosed
US-9957260-B2 Organic metal complex, light emitting material, delayed fluorescent material, and organic light emitting device KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2018-05-01 US disclosed
CN-106749094-A 42 (2` hydroxy phenyls) benzoxazole compounds and its preparation method and purposes containing substituted base 南京邮电大学 2017-05-31 CN disclosed
US-20160185765-A1 ORGANIC METAL COMPLEX, LIGHT EMITTING MATERIAL, DELAYED FLUORESCENT MATERIAL, AND ORGANIC LIGHT EMITTING DEVICE DYDEN CO (JP) 2016-06-30 US disclosed
US-20160185765-A1 ORGANIC METAL COMPLEX, LIGHT EMITTING MATERIAL, DELAYED FLUORESCENT MATERIAL, AND ORGANIC LIGHT EMITTING DEVICE DYDEN CO (JP) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329100-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME SAT1, SLC1A2, SLC18A1 KDM6B 1748/4885KDM6A 1905/4885MAPT 2202/4885
US-20160185765-A1 ORGANIC METAL COMPLEX, LIGHT EMITTING MATERIAL, DELAYED FLUORESCENT MATERIAL, AND ORGANIC LIGHT EMITTING DEVICE OR10J3, SOD1, H1-10 KDM6B 2444/4885KDM6A 2468/4885MAPT 3159/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.