Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 4/20 | 0.79 |
| ▸ | ADRA2C | P18825 | 6/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.63 |
| ▸ | CFB | P00751 | 5/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.63 |
| ▸ | HTR1B | P28222 | 3/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 8/20 | 0.59 |
| ▸ | ADRA2B | P18089 | 5/20 | 0.59 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.59 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.56 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | HRH2 | P25021 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4760243 | 0.89 | HTR1D (1.00) | HTR1DADRA2CADRA1ACFBKCNH2 | |
| SCHEMBL11182818 | 0.89 | ADRA2C (0.65) | HTR1DADRA2CADRA1ACFBKCNH2 | |
| Hydrochloric Acid SCHEMBL11857722 | 0.87 | ADRA2C (0.66) | HTR1DADRA2CADRA1ACFBKCNH2 | |
| Hydrochloric Acid SCHEMBL29384552 | 0.87 | HTR1D (0.97) | HTR1DADRA2CADRA1ACFBKCNH2 | |
| SCHEMBL11176814 | 0.82 | ADRA2A (0.79) | HTR1DADRA2CADRA1ACFBKCNH2 | |
| Romifidine SCHEMBL246009 | 0.82 | ADRA2C (0.56) | HTR1DADRA2CADRA1ACFBKCNH2 | |
| Romifidine SCHEMBL29761110 | 0.82 | ADRA2C (0.56) | HTR1DADRA2CADRA1ACFBKCNH2 | |
| Romifidine SCHEMBL1970327 | 0.81 | ADRA2C (0.57) | HTR1DADRA2CADRA1ACFBKCNH2 | |
| Romifidine SCHEMBL22616284 | 0.81 | ADRA2C (0.55) | HTR1DADRA2CADRA1ACFBKCNH2 | |
| SCHEMBL4761560 | 0.79 | HTR1D (0.75) | HTR1DADRA2CADRA1ACFBKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016105448-A1 | IMIDAZOLINE RECEPTOR TYPE 1 LIGANDS FOR USE AS THERAPEUTICS | RIDEOUT DARRYL (US) | 2016-06-30 | — | — | WO | disclosed |