Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.71 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PPID | Q08752 | 1/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.51 |
| ▸ | CFD | P00746 | 1/20 | 0.50 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.50 |
| ▸ | PADI3 | Q9ULW8 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL714625 | 0.86 | EPHX1 (0.77) | EPHX1EPHX2SMN1; SMN2TP53LMNA | |
| SCHEMBL27771414 | 0.85 | EPHX1 (0.71) | EPHX1EPHX2SMN1; SMN2TP53MEN1 | |
| SCHEMBL6435482 | 0.85 | EPHX2 (0.83) | EPHX1EPHX2SMN1; SMN2TP53LMNA | |
| SCHEMBL6436792 | 0.83 | EPHX2 (0.80) | EPHX1EPHX2SMN1; SMN2TP53LMNA | |
| SCHEMBL3418508 | 0.83 | EPHX1 (1.00) | EPHX1EPHX2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7916928 | 0.83 | EPHX1 (0.73) | EPHX1EPHX2SMN1; SMN2TP53LMNA | |
| SCHEMBL6436358 | 0.83 | EPHX2 (0.80) | EPHX1EPHX2SMN1; SMN2TP53LMNA | |
| SCHEMBL6438376 | 0.83 | EPHX2 (0.80) | EPHX1EPHX2SMN1; SMN2TP53LMNA | |
| SCHEMBL27673646 | 0.82 | MEN1 (0.50) | EPHX1EPHX2SMN1; SMN2LMNAPTPN1 | |
| SCHEMBL11704793 | 0.82 | NAMPT (0.56) | EPHX1SMN1; SMN2MEN1KMT2AP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110124647-A1 | INSECTICIDAL DERIVATIVES OF SUBSTITUTED BENZYLAMINES | BAYER CROPSCIENCE AG (DE) | 2011-05-26 | — | — | US | disclosed |
| CN-101652070-A | insecticidal derivatives of substituted benzylamines | BAYER CROPSCIENCE AG DE | 2010-02-17 | — | — | CN | disclosed |
| EP-2144505-A1 | INSECTICIDAL DERIVATIVES OF SUBSTITUTED BENZYLAMINES | Bayer CropScience AG (DE) | 2010-01-20 | — | — | EP | disclosed |
| WO-2008119506-A2 | INSECTICIDAL DERIVATIVES OF SUBSTITUTED PHENYLALKYLAMINES | BAYER CROPSCIENCE AG (DE) | 2008-10-09 | — | — | WO | disclosed |
| WO-2008119511-A1 | INSECTICIDAL DERIVATIVES OF SUBSTITUTED BENZYLAMINES | BAYER CROPSCIENCE AG (DE) | 2008-10-09 | — | — | WO | disclosed |
| EP-1977644-A1 | Insecticidal derivatives of substituted benzylamines | Bayer CropScience Aktiengesellschaft (DE) | 2008-10-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124647-A1 | INSECTICIDAL DERIVATIVES OF SUBSTITUTED BENZYLAMINES | BCHE, PNMT, TMBIM6 | EPHX1 1236/4885EPHX2 1091/4885SMN1; SMN2 1073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.