Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL17894405 | 0.90 | NR4A2 (0.51) | BCHE | |
| SCHEMBL17894552 | 0.89 | BCHE (0.63) | MRGPRX1PRSS1PRSS2PRSS3BCHE | |
| Hydrochloric Acid SCHEMBL8202366 | 0.88 | MRGPRX1 (0.61) | MRGPRX1PRSS1PRSS2PRSS3BCHE | |
| Trifluoroacetic Acid SCHEMBL17894393 | 0.88 | HDAC3 (0.53) | BCHE | |
| Trifluoroacetic Acid SCHEMBL17894475 | 0.88 | GID4 (0.61) | — | |
| Trifluoroacetic Acid SCHEMBL5172108 | 0.87 | HDAC3 (0.52) | — | |
| Trifluoroacetic Acid SCHEMBL17894408 | 0.85 | MAOB (0.47) | — | |
| Trifluoroacetic Acid SCHEMBL17894479 | 0.84 | KMT2A (0.53) | BCHE | |
| Trifluoroacetic Acid SCHEMBL17894392 | 0.84 | LTA4H (0.61) | — | |
| Trifluoroacetic Acid SCHEMBL17894468 | 0.83 | NR4A2 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170342025-A1 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS AND METHODS | THE UNIVERSITY OF BATH (GB) | 2017-11-30 | — | — | US | disclosed |
| EP-3240775-A2 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS AND METHODS | Swansea University (GB) | 2017-11-08 | — | — | EP | disclosed |
| WO-2016108045-A2 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS AND METHODS | SWANSEA UNIVERSITY (GB) | 2016-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170342025-A1 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS AND METHODS | ZYX, MPO, CFB | MRGPRX1 365/4885PRSS1 2260/4885PRSS2 2297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.