Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | KLK1 | P06870 | 2/20 | 0.50 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NAMPT | P43490 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 4/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TMPRSS6 | Q8IU80 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19639325 | 0.92 | MEN1 (0.57) | NPC1RAB9AKDM4EMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL17894404 | 0.90 | EPHX2 (0.53) | RAB9AKLK1KLK5NAMPTEPHX2 | |
| Trifluoroacetic Acid SCHEMBL17894369 | 0.87 | ITGB3 (0.55) | NPC1RAB9AKMT2ANR1H4F2 | |
| SCHEMBL10644987 | 0.87 | NAMPT (0.58) | NPC1RAB9AKLK1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL10606782 | 0.85 | F2 (0.57) | NPC1RAB9AKLK1MEN1KMT2A | |
| SCHEMBL24892110 | 0.85 | KMT2A (0.56) | NPC1RAB9AKDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10616924 | 0.84 | F2 (0.56) | NPC1RAB9AKLK1MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL5172108 | 0.84 | HDAC3 (0.52) | MEN1KMT2AF2TMPRSS6 | |
| SCHEMBL30180871 | 0.81 | KMT2A (0.63) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL17894494 | 0.81 | HDAC1 (0.59) | KDM4EMEN1KMT2ANAMPTEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170342025-A1 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS AND METHODS | THE UNIVERSITY OF BATH (GB) | 2017-11-30 | — | — | US | disclosed |
| EP-3240775-A2 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS AND METHODS | Swansea University (GB) | 2017-11-08 | — | — | EP | disclosed |
| WO-2016108045-A2 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS AND METHODS | SWANSEA UNIVERSITY (GB) | 2016-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170342025-A1 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS AND METHODS | ZYX, MPO, CFB | NPC1 903/4885RAB9A 1751/4885KLK1 1221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.