Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | NAMPT | P43490 | 5/20 | 0.49 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | KLK1 | P06870 | 1/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.46 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17894494 | 0.92 | HDAC1 (0.59) | EPHX2NR1H4HDAC1HDAC6HDAC3 | |
| Trifluoroacetic Acid SCHEMBL17894363 | 0.90 | NPC1 (0.52) | EPHX2NR1H4NAMPTKLK1KLK5 | |
| SCHEMBL19639325 | 0.81 | MEN1 (0.57) | NR1H4HDAC1HDAC6NAMPTMAPT | |
| SCHEMBL7303517 | 0.81 | NR1H4 (0.61) | EPHX2NR1H4HDAC1HDAC6TPSAB1 | |
| SCHEMBL7294446 | 0.80 | EPHX2 (0.52) | EPHX2NR1H4HDAC1HDAC6TPSAB1 | |
| Hydrochloric Acid SCHEMBL9264373 | 0.80 | NR1H4 (0.60) | EPHX2NR1H4HDAC1HDAC6TPSAB1 | |
| Phenylguanidine SCHEMBL7425328 | 0.79 | CHIT1 (0.49) | EPHX2HDAC1HDAC6HDAC3KLK1 | |
| SCHEMBL8041030 | 0.79 | USP30 (0.48) | HDAC1HDAC6HDAC3 | |
| SCHEMBL6681065 | 0.79 | HDAC6 (0.59) | EPHX2NR1H4HDAC1HDAC6HDAC3 | |
| Trifluoroacetic Acid SCHEMBL7417053 | 0.78 | ITGB3 (0.53) | KLK1KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170342025-A1 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS AND METHODS | THE UNIVERSITY OF BATH (GB) | 2017-11-30 | — | — | US | disclosed |
| EP-3240775-A2 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS AND METHODS | Swansea University (GB) | 2017-11-08 | — | — | EP | disclosed |
| WO-2016108045-A2 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS AND METHODS | SWANSEA UNIVERSITY (GB) | 2016-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170342025-A1 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS AND METHODS | ZYX, MPO, CFB | EPHX2 1023/4885NR1H4 1013/4885HDAC1 1517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.