Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.52 |
| ▸ | CNR1 | P21554 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.50 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28607116 | 1.00 | EPHX2 (0.52) | EPHX2CNR1ALDH1A1HPGDSLC6A5 | |
| SCHEMBL13583973 | 0.93 | FAAH (0.47) | EPHX2CNR1ALDH1A1 | |
| SCHEMBL28769324 | 0.93 | FAAH (0.47) | EPHX2CNR1ALDH1A1 | |
| SCHEMBL23440261 | 0.91 | CNR1 (0.55) | EPHX2CNR1ALDH1A1HPGDSLC6A5 | |
| SCHEMBL21240005 | 0.89 | EPHX2 (0.63) | EPHX2CNR1ALDH1A1HPGDSLC6A5 | |
| Sulfuric Acid SCHEMBL29001433 | 0.84 | CNR1 (0.60) | EPHX2CNR1ALDH1A1HPGDSLC6A5 | |
| SCHEMBL439627 | 0.83 | NAAA (0.46) | CNR1ALDH1A1HPGDTRPV1MEN1 | |
| SCHEMBL11521072 | 0.83 | ALDH1A1 (0.50) | EPHX2CNR1ALDH1A1MEN1KMT2A | |
| SCHEMBL8608004 | 0.82 | EPHX2 (0.52) | EPHX2CNR1ALDH1A1HPGDSLC6A5 | |
| SCHEMBL6562430 | 0.82 | EPHX2 (0.52) | EPHX2CNR1ALDH1A1HPGDSLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11021573-B2 | Polyimide-forming compositions, methods of manufacture, and articles prepared therefrom | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2021-06-01 | — | — | US | disclosed |
| US-20190233589-A1 | POLYIMIDE-FORMING COMPOSITIONS, METHODS OF MANUFACTURE, AND ARTICLES PREPARED THEREFROM | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2019-08-01 | — | — | US | disclosed |
| US-10294329-B2 | Polyimide-forming compositions, methods of manufacture, and articles prepared therefrom | SABIC GLOBAL TECHNOLOGIES B.V. | 2019-05-21 | — | — | US | disclosed |
| US-20180215871-A1 | LASER-INITIATED ADDITIVE MANUFACTURING OF POLYIMIDE PRECURSOR | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2018-08-02 | — | — | US | disclosed |
| EP-3310716-A1 | SURFACTANT REMOVAL FROM PRODUCED WATERS | ConocoPhillips Company (US) | 2018-04-25 | — | — | EP | disclosed |
| EP-3303449-A1 | LASER-INITIATED ADDITIVE MANUFACTURING OF POLYIMIDE PRECURSOR | SABIC Global Technologies B.V. (NL) | 2018-04-11 | — | — | EP | disclosed |
| US-20170362384-A1 | POLYIMIDE-FORMING COMPOSITIONS, METHODS OF MANUFACTURE, AND ARTICLES PREPARED THEREFROM | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2017-12-21 | — | — | US | disclosed |
| EP-3240843-A1 | POLYIMIDE-FORMING COMPOSITIONS, METHODS OF MANUFACTURE, AND ARTICLES PREPARED THEREFROM | SABIC Global Technologies B.V. (NL) | 2017-11-08 | — | — | EP | disclosed |
| US-20160368786-A1 | SURFACTANT REMOVAL FROM PRODUCED WATERS | CONOCOPHILLIPS COMPANY | 2016-12-22 | — | — | US | disclosed |
| WO-2016193932-A1 | LASER-INITIATED ADDITIVE MANUFACTURING OF POLYIMIDE PRECURSOR | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2016-12-08 | — | — | WO | disclosed |
| WO-2016109343-A1 | POLYIMIDE-FORMING COMPOSITIONS, METHODS OF MANUFACTURE, AND ARTICLES PREPARED THEREFROM | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2016-07-07 | — | — | WO | disclosed |