Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 3/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.39 |
| ▸ | PI4KA | P42356 | 2/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.39 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17895688 | 0.82 | PIK3CG (0.38) | PIK3CGPIK3CDPIK3CARAB9ACSNK1D | |
| SCHEMBL17895558 | 0.80 | RORC (0.37) | RAB9ACSNK1DRORCNPC1CYP1A2 | |
| SCHEMBL17895681 | 0.80 | NPC1 (0.38) | PIK3CDRAB9ACSNK1DNPC1CYP1A2 | |
| SCHEMBL17895651 | 0.78 | RAB9A (0.36) | RAB9ACSNK1DNPC1CYP1A2CYP3A4 | |
| SCHEMBL17895568 | 0.78 | CSNK1D (0.38) | RAB9ACSNK1DPDE5APDE4DPDE7A | |
| SCHEMBL17895612 | 0.77 | CSNK1D (0.41) | RAB9ACSNK1DKCNH2NPC1CYP1A2 | |
| SCHEMBL17895710 | 0.75 | RAB9A (0.36) | RAB9ACSNK1DNPC1CYP1A2CYP3A4 | |
| SCHEMBL17895727 | 0.75 | RAB9A (0.36) | RAB9ACSNK1DNPC1CYP1A2CYP3A4 | |
| SCHEMBL17895677 | 0.75 | RAB9A (0.36) | RAB9ACSNK1DNPC1CYP1A2CYP3A4 | |
| SCHEMBL17895599 | 0.75 | PPARA (0.38) | PIK3CDRAB9ACSNK1DRORCNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531631-B | Methods and agents for treating diseases | 安吉昂生物医药公司 | 2021-09-03 | — | — | CN | claimed |
| CN-107531631-B | Methods and agents for treating diseases | 安吉昂生物医药公司 | 2021-09-03 | — | — | CN | disclosed |
| EP-3240778-A1 | METHODS AND AGENTS FOR TREATING DISEASE | Angion Biomedica Corp. (US) | 2017-11-08 | — | — | EP | disclosed |
| WO-2016109492-A1 | METHODS AND AGENTS FOR TREATING DISEASE | ANGION BIOMEDICA CORP (US) | 2016-07-07 | — | — | WO | disclosed |