Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | CASR | P41180 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17895681 | 0.91 | NPC1 (0.38) | RAB9ANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17895688 | 0.86 | PIK3CG (0.38) | RAB9ANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17895599 | 0.85 | PPARA (0.38) | RAB9ANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17895558 | 0.85 | RORC (0.37) | RAB9ANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17895611 | 0.84 | PIK3CA (0.39) | RAB9ANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17895701 | 0.78 | TUBB4A (0.36) | RAB9ANPC1DYRK1APPARACASR | |
| SCHEMBL17895608 | 0.78 | PIK3CG (0.39) | RAB9ANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17895705 | 0.76 | RORC (0.39) | RAB9ANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17895719 | 0.75 | PPARA (0.36) | RAB9ANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17895612 | 0.75 | CSNK1D (0.41) | RAB9ANPC1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531631-B | Methods and agents for treating diseases | 安吉昂生物医药公司 | 2021-09-03 | — | — | CN | claimed |
| EP-3240778-A1 | METHODS AND AGENTS FOR TREATING DISEASE | Angion Biomedica Corp. (US) | 2017-11-08 | — | — | EP | claimed |
| WO-2016109492-A1 | METHODS AND AGENTS FOR TREATING DISEASE | ANGION BIOMEDICA CORP (US) | 2016-07-07 | — | — | WO | claimed |
| CN-107531631-B | Methods and agents for treating diseases | 安吉昂生物医药公司 | 2021-09-03 | — | — | CN | disclosed |
| EP-3240778-A1 | METHODS AND AGENTS FOR TREATING DISEASE | Angion Biomedica Corp. (US) | 2017-11-08 | — | — | EP | disclosed |
| WO-2016109492-A1 | METHODS AND AGENTS FOR TREATING DISEASE | ANGION BIOMEDICA CORP (US) | 2016-07-07 | — | — | WO | disclosed |