Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | FABP4 | P15090 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17896002 | 0.91 | LMNA (0.38) | TSHRALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL17895823 | 0.85 | LMNA (0.35) | TSHRALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL17895906 | 0.80 | NOTUM (0.38) | TSHRALDH1A1KDM4EGAAHPGD | |
| SCHEMBL17895839 | 0.76 | PLK1 (0.47) | TSHRALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL17896114 | 0.75 | HSD11B1 (0.36) | TSHRALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL17896006 | 0.74 | LMNA (0.38) | TSHRALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL17896080 | 0.74 | LMNA (0.41) | TSHRALDH1A1KDM4EMAPTGAA | |
| SCHEMBL17896153 | 0.73 | LMNA (0.37) | TSHRALDH1A1KDM4ETDP1MAPT | |
| SCHEMBL17895886 | 0.73 | ELANE (0.34) | MAPTLMNAHTTUSP2L3MBTL1 | |
| SCHEMBL17896049 | 0.72 | LMNA (0.35) | TSHRALDH1A1KDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109706-A1 | FUSED POLYCYCLIC 2-PYRIDINONE ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-07-07 | — | — | WO | claimed |
| WO-2016109706-A1 | FUSED POLYCYCLIC 2-PYRIDINONE ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-07-07 | — | — | WO | disclosed |