Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17896107 | 0.94 | USP2 (0.34) | USP2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL17895841 | 0.88 | ELANE (0.32) | ELANESPR | |
| SCHEMBL17896061 | 0.88 | ALDH1A1 (0.37) | ALDH1A1ELANEKDM4ESPR | |
| SCHEMBL17895886 | 0.87 | ELANE (0.34) | USP2MAPTLMNAELANEL3MBTL1 | |
| SCHEMBL17901948 | 0.87 | KDM4E (0.33) | USP2ALDH1A1MAPTLMNAELANE | |
| Hydrochloric Acid SCHEMBL17896128 | 0.87 | ALDH1A1 (0.37) | ALDH1A1ELANEL3MBTL1KDM4ESPR | |
| SCHEMBL17896114 | 0.85 | HSD11B1 (0.36) | USP2ALDH1A1MAPTLMNAHPGD | |
| SCHEMBL17896093 | 0.85 | ALDH1A1 (0.38) | ALDH1A1MAPTLMNAELANEKDM4E | |
| SCHEMBL17895850 | 0.84 | KDM4E (0.35) | MAPTLMNAELANEKDM4ESPR | |
| Hydrochloric Acid SCHEMBL17896096 | 0.84 | ALDH1A1 (0.37) | ALDH1A1ELANEKDM4ESPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109706-A1 | FUSED POLYCYCLIC 2-PYRIDINONE ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-07-07 | — | — | WO | claimed |
| WO-2016109706-A1 | FUSED POLYCYCLIC 2-PYRIDINONE ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-07-07 | — | — | WO | disclosed |