Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SPR | P35270 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17896048 | 0.94 | USP2 (0.33) | USP2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL17895886 | 0.89 | ELANE (0.34) | USP2MAPTLMNAELANEHTT | |
| SCHEMBL17896114 | 0.87 | HSD11B1 (0.36) | USP2ALDH1A1MAPTLMNAHPGD | |
| SCHEMBL17896093 | 0.86 | ALDH1A1 (0.38) | ALDH1A1MAPTLMNAELANEKDM4E | |
| SCHEMBL17895841 | 0.86 | ELANE (0.32) | ELANESPR | |
| SCHEMBL17895850 | 0.86 | KDM4E (0.35) | MAPTLMNAELANEKDM4ESPR | |
| Hydrochloric Acid SCHEMBL17896096 | 0.85 | ALDH1A1 (0.37) | ALDH1A1ELANEKDM4ESPRPLK1 | |
| SCHEMBL17896061 | 0.85 | ALDH1A1 (0.37) | ALDH1A1ELANEKDM4ESPRPLK1 | |
| Hydrochloric Acid SCHEMBL17895964 | 0.85 | KDM4E (0.35) | ALDH1A1MAPTKMT2ALMNAHSD17B10 | |
| Hydrochloric Acid SCHEMBL17896128 | 0.85 | ALDH1A1 (0.37) | ALDH1A1ELANEKDM4ESPRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109706-A1 | FUSED POLYCYCLIC 2-PYRIDINONE ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-07-07 | — | — | WO | claimed |
| WO-2016109706-A1 | FUSED POLYCYCLIC 2-PYRIDINONE ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-07-07 | — | — | WO | disclosed |