Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | PDE5A | O76074 | 3/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17895933 | 0.99 | ALDH1A1 (0.35) | ALDH1A1POLBAPEX1RECQLTDP1 | |
| SCHEMBL17895916 | 0.82 | LMNA (0.32) | ALDH1A1POLBAPEX1RECQLTDP1 | |
| Hydrochloric Acid SCHEMBL17896058 | 0.81 | LMNA (0.32) | ALDH1A1POLBAPEX1RECQLTDP1 | |
| SCHEMBL17896007 | 0.81 | LMNA (0.37) | ALDH1A1POLBAPEX1RECQLTDP1 | |
| Hydrochloric Acid SCHEMBL17896090 | 0.80 | LMNA (0.36) | ALDH1A1POLBAPEX1RECQLTDP1 | |
| SCHEMBL17895831 | 0.80 | LMNA (0.36) | ALDH1A1POLBAPEX1RECQLTDP1 | |
| Hydrochloric Acid SCHEMBL17895824 | 0.79 | LMNA (0.35) | ALDH1A1POLBLMNAUSP2KDM4E | |
| SCHEMBL17896099 | 0.79 | PDE5A (0.42) | ALDH1A1POLBLMNAKDM4ETSHR | |
| SCHEMBL17896150 | 0.79 | LMNA (0.30) | LMNA | |
| Hydrochloric Acid SCHEMBL17896146 | 0.78 | PDE5A (0.42) | ALDH1A1POLBLMNAKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109706-A1 | FUSED POLYCYCLIC 2-PYRIDINONE ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-07-07 | — | — | WO | claimed |
| WO-2016109706-A1 | FUSED POLYCYCLIC 2-PYRIDINONE ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-07-07 | — | — | WO | disclosed |