Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17895856 | 0.99 | LMNA (0.33) | LMNAHPGDHSD17B10ALDH1A1MAPT | |
| SCHEMBL17895834 | 0.89 | ALDH1A1 (0.32) | LMNAHPGDALDH1A1KDM4EHTT | |
| Hydrochloric Acid SCHEMBL17896125 | 0.88 | ALDH1A1 (0.31) | HPGDALDH1A1KDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL17895875 | 0.87 | HPGD (0.34) | LMNAHPGDHSD17B10ALDH1A1MAPT | |
| SCHEMBL17896017 | 0.86 | LMNA (0.34) | LMNAHSD17B10ALDH1A1MAPTPOLB | |
| SCHEMBL17896034 | 0.84 | LMNA (0.35) | LMNAALDH1A1KDM4EUSP2TSHR | |
| SCHEMBL17896133 | 0.84 | ALDH1A1 (0.36) | LMNAHPGDALDH1A1POLBKDM4E | |
| SCHEMBL17896121 | 0.84 | LMNA (0.34) | LMNAHPGDALDH1A1MAPTPOLB | |
| SCHEMBL17895780 | 0.83 | LMNA (0.34) | LMNAHPGDALDH1A1MAPTPOLB | |
| SCHEMBL17896074 | 0.82 | LMNA (0.32) | LMNAALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109706-A1 | FUSED POLYCYCLIC 2-PYRIDINONE ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-07-07 | — | — | WO | claimed |
| WO-2016109706-A1 | FUSED POLYCYCLIC 2-PYRIDINONE ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-07-07 | — | — | WO | disclosed |