Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 4/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.31 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.31 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 2/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17895780 | 0.93 | LMNA (0.34) | LMNAKDM4ETSHRALDH1A1MAPT | |
| SCHEMBL17895925 | 0.91 | LMNA (0.33) | LMNAKDM4ETSHRALDH1A1MAPT | |
| SCHEMBL17896017 | 0.90 | LMNA (0.34) | LMNAKDM4ETSHRALDH1A1MAPT | |
| SCHEMBL17896005 | 0.90 | KDM4E (0.34) | LMNAKDM4ETSHRALDH1A1MAPT | |
| SCHEMBL17896071 | 0.90 | ALDH1A1 (0.34) | LMNAKDM4ETSHRALDH1A1PKM | |
| SCHEMBL17896063 | 0.90 | TSHR (0.35) | LMNAKDM4ETSHRALDH1A1MAPT | |
| SCHEMBL17895973 | 0.89 | LMNA (0.32) | LMNAKDM4ETSHRALDH1A1PKM | |
| Hydrochloric Acid SCHEMBL17896047 | 0.89 | TSHR (0.34) | LMNAKDM4ETSHRALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL17895890 | 0.89 | ALDH1A1 (0.33) | LMNAKDM4ETSHRALDH1A1PKM | |
| Hydrochloric Acid SCHEMBL17896027 | 0.89 | ALDH1A1 (0.33) | LMNAKDM4ETSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109706-A1 | FUSED POLYCYCLIC 2-PYRIDINONE ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-07-07 | — | — | WO | claimed |