Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.48 |
| ▸ | CTSS | P25774 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | REN | P00797 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 5/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3220161 | 1.00 | CTSK (0.48) | CTSKCTSSCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3685468 | 1.00 | CTSK (0.48) | CTSKCTSSCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11522699 | 0.89 | CTSK (0.46) | CTSKCTSSCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11691694 | 0.87 | CTSK (0.45) | CTSKCTSSCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14217667 | 0.87 | CTSK (0.45) | CTSKCTSSCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5027594 | 0.87 | CTSK (0.45) | CTSKCTSSCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7158579 | 0.87 | CTSK (0.45) | CTSKCTSSCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9779450 | 0.86 | CTSK (0.45) | CTSKCTSSCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3224065 | 0.85 | CTSK (0.43) | CTSKCTSSCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9779446 | 0.83 | CTSS (0.51) | CTSKCTSSCYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110512198-A | A kind of chemical bronze plating liquid, chemical plating copper film and preparation method thereof | SUZHOU SKYCHEM LTD | 2019-11-29 | — | — | CN | claimed |
| EP-4332089-A1 | METHOD FOR PREPARING AMINO ACIDS | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2024-03-06 | — | — | EP | disclosed |
| CN-110512198-A | A kind of chemical bronze plating liquid, chemical plating copper film and preparation method thereof | SUZHOU SKYCHEM LTD | 2019-11-29 | — | — | CN | disclosed |
| EP-3303328-B1 | AMINOESTER DERIVATIVES | CHIESI FARM SPA (IT) | 2019-03-20 | — | — | EP | disclosed |
| EP-3077385-B1 | HETEROARYL DERIVATIVES FOR THE TREATMENT OF RESPIRATORY DISEASES | CHIESI FARM SPA (IT) | 2017-10-04 | — | — | EP | disclosed |
| EP-3077385-B1 | HETEROARYL DERIVATIVES FOR THE TREATMENT OF RESPIRATORY DISEASES | CHIESI FARM SPA (IT) | 2017-10-04 | — | — | EP | disclosed |
| US-9636336-B2 | Aminoester derivatives | CHIESI FARMACEUTICI S.P.A. (IT) | 2017-05-02 | — | — | US | disclosed |
| US-20160346268-A1 | AMINOESTER DERIVATIVES | CHIESI FARMACEUTICI S.P.A. (IT) | 2016-12-01 | — | — | US | disclosed |
| EP-2643295-B1 | GLYCINE DERIVATIVES AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | CHIESI FARMA SPA (IT) | 2016-04-13 | — | — | EP | disclosed |
| EP-2643295-B1 | GLYCINE DERIVATIVES AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | CHIESI FARMA SPA (IT) | 2016-04-13 | — | — | EP | disclosed |
| EP-0951466-A2 | CYCLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS | Elan Pharmaceuticals, Inc. (US) | 1999-10-27 | — | — | EP | disclosed |
| WO-1998028268-A2 | CYCLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS AS β-AMYLOID PEPTIDE RELEASE INHIBITORS | ELAN PHARMACEUTICALS, INC. (US) | 1998-07-02 | — | — | WO | disclosed |
| US-4735937-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-04-05 | — | — | US | disclosed |
| US-4463172-A | Process for producing 2-methyl cephem-2-em and 2-methylcephem-3-em derivitaves | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-07-31 | — | — | US | disclosed |
| US-4430498-A | 8-Oxo-5-thia-1-azabicyclo(4,2,0)oct-2-ene compounds | CIBA-GEIGY CORPORATION (US) | 1984-02-07 | — | — | US | disclosed |
| US-4405778-A | Process for preparing cephalosporin ethers | CIBA-GEIGY CORPORATION (US) | 1983-09-20 | — | — | US | disclosed |
| US-4385176-A | RING EXPANSION USING A LEWIS ACID | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-05-24 | — | — | US | disclosed |
| US-4308380-A | 2-Lower alkyl-2 or 3-cephem-4-carboxylic acid derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-12-29 | — | — | US | disclosed |
| EP-0035357-A1 | 2-Methylcephalosporins and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1981-09-09 | — | — | EP | disclosed |
| US-4113940-A | ANTIMICROBIAL | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1978-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160346268-A1 | AMINOESTER DERIVATIVES | PDE4A, PDE4B, PDE3B | CTSK 2607/4885CTSS 2198/4885CYP3A4 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.