Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 13/20 | 0.51 |
| ▸ | CTSK | P43235 | 12/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 3/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3685468 | 0.83 | CTSK (0.48) | CTSSCTSKCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1789747 | 0.83 | CTSK (0.48) | CTSSCTSKCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3220161 | 0.83 | CTSK (0.48) | CTSSCTSKCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11388207 | 0.81 | CTSS (0.74) | CTSSCTSKCTSLCTSBATM | |
| SCHEMBL11522699 | 0.81 | CTSK (0.46) | CTSSCTSKCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14217667 | 0.80 | CTSK (0.45) | CTSSCTSKCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11691694 | 0.80 | CTSK (0.45) | CTSSCTSKCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7158579 | 0.80 | CTSK (0.45) | CTSSCTSKCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5027594 | 0.80 | CTSK (0.45) | CTSSCTSKCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9779450 | 0.79 | CTSK (0.45) | CTSSCTSKCYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015659-A | Cognition activators to slow aging of the brain | CASSELLA AKTIENGESELLSCHAFT (DE) | 1991-05-14 | — | — | US | disclosed |