Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 8/20 | 0.46 |
| ▸ | CTSS | P25774 | 5/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 2/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17771364 | 1.00 | MEN1 (0.49) | MEN1GAAKMT2AALDH1A1TSHR | |
| SCHEMBL17898605 | 0.90 | CA1 (0.44) | MEN1GAAKMT2AALDH1A1TSHR | |
| SCHEMBL2211809 | 0.87 | FOLH1 (0.58) | MEN1GAAKMT2AALDH1A1TSHR | |
| SCHEMBL12643955 | 0.87 | FOLH1 (0.58) | MEN1GAAKMT2AALDH1A1TSHR | |
| SCHEMBL7718173 | 0.87 | FOLH1 (0.58) | MEN1GAAKMT2AALDH1A1TSHR | |
| SCHEMBL3445777 | 0.86 | MEN1 (0.65) | MEN1GAAKMT2AALDH1A1TSHR | |
| SCHEMBL10241524 | 0.86 | MEN1 (0.65) | MEN1GAAKMT2AALDH1A1TSHR | |
| SCHEMBL391537 | 0.86 | MEN1 (0.65) | MEN1GAAKMT2AALDH1A1TSHR | |
| SCHEMBL16521928 | 0.85 | CA1 (0.48) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL20143076 | 0.85 | MEN1 (0.55) | MEN1GAAKMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160194278-A1 | DITHIOL MUCOLYTIC AGENTS | PARION SCIENCES, INC. (US) | 2016-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160194278-A1 | DITHIOL MUCOLYTIC AGENTS | MUC1, DNASE1, MMP8 | MEN1 3223/4885GAA 122/4885KMT2A 4277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.