Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21985739 | 0.84 | PPARG (0.41) | GPR34PPARGPPARATRPA1RCE1 | |
| SCHEMBL17896162 | 0.84 | PPARG (0.41) | GPR34PPARGPPARATRPA1RCE1 | |
| SCHEMBL17898733 | 0.78 | RCE1 (0.40) | SLC6A2SLC6A4SLC6A3TRPA1SIGMAR1 | |
| SCHEMBL19039692 | 0.75 | CACNA1B (0.40) | PPARGPPARA | |
| SCHEMBL17896224 | 0.73 | PPARG (0.44) | SLC6A4PPARGPPARASIGMAR1RCE1 | |
| SCHEMBL17896225 | 0.72 | PPARG (0.38) | SLC6A4SLC6A3GPR34PPARGPPARA | |
| SCHEMBL19760187 | 0.71 | TRPA1 (0.44) | SLC6A4PPARGPPARATRPA1 | |
| SCHEMBL19758129 | 0.71 | TRPA1 (0.44) | SLC6A4PPARGPPARATRPA1 | |
| SCHEMBL16594144 | 0.71 | TAS2R14 (0.36) | SLC6A4PPARGPPARA | |
| SCHEMBL17904939 | 0.70 | PPARA (0.39) | SLC6A4GPR34PPARGPPARATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180002319-A1 | MACROCYCLIC PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2018-01-04 | — | — | US | disclosed |
| US-20180002320-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2018-01-04 | — | — | US | disclosed |
| WO-2016109291-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109290-A1 | MACROCYCLIC PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180002320-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | CYP4F12, CYP1A2, CYP4F2 | SLC6A2 3110/4885SLC6A4 2301/4885SLC6A3 2621/4885 |
| US-20180002319-A1 | MACROCYCLIC PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | AADAC, CYP51A1, PFAS | SLC6A2 4015/4885SLC6A4 3189/4885SLC6A3 3954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.