Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16605191 | 0.98 | TAS1R3 (0.33) | TAS1R3TAS1R1ABCB1CTSKRIPK1 | |
| SCHEMBL16605203 | 0.92 | HPGDS (0.32) | — | |
| SCHEMBL16605214 | 0.92 | — | — | |
| SCHEMBL16605185 | 0.91 | HCRTR1 (0.33) | TAS1R3TAS1R1RIPK1HCRTR1 | |
| SCHEMBL17898782 | 0.91 | RIPK1 (0.33) | RIPK1 | |
| SCHEMBL17898764 | 0.91 | RIPK1 (0.33) | CTSKRIPK1 | |
| SCHEMBL16605196 | 0.90 | TAS1R3 (0.35) | TAS1R3TAS1R1RIPK1ADORA2AHCRTR1 | |
| SCHEMBL16605197 | 0.90 | TAS1R3 (0.35) | TAS1R3TAS1R1RIPK1ADORA2AHCRTR1 | |
| SCHEMBL15530250 | 0.90 | ABCB1 (0.31) | ABCB1RIPK1 | |
| SCHEMBL15366272 | 0.90 | ABCB1 (0.31) | ABCB1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109291-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109290-A1 | MACROCYCLIC PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |