Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 8/20 | 0.38 |
| ▸ | BACE1 | P56817 | 6/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16605410 | 0.88 | GAA (0.36) | GAACTSDBACE1 | |
| SCHEMBL17903383 | 0.87 | KMT2A (0.37) | GAA | |
| SCHEMBL17898862 | 0.86 | GAA (0.34) | GAACTSD | |
| SCHEMBL19089218 | 0.86 | GAA (0.46) | GAACTSDBACE1 | |
| SCHEMBL19091112 | 0.85 | GAA (0.42) | GAACTSDBACE1 | |
| SCHEMBL17898912 | 0.85 | GAA (0.40) | GAACTSDBACE1 | |
| SCHEMBL17899063 | 0.84 | GAA (0.39) | GAACTSDBACE1 | |
| SCHEMBL17898754 | 0.83 | KMT2A (0.38) | GAA | |
| SCHEMBL17898811 | 0.82 | GAA (0.38) | GAACTSDBACE1 | |
| SCHEMBL19628405 | 0.82 | GAA (0.42) | GAACTSDBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109290-A1 | MACROCYCLIC PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109291-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |