Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19628393 | 0.87 | KMT2A (0.36) | NAAA | |
| SCHEMBL19628410 | 0.86 | GAA (0.35) | GAACTSDNFKB1NFKB2RELA | |
| SCHEMBL19628409 | 0.86 | GAA (0.35) | GAA | |
| SCHEMBL19628403 | 0.86 | GAA (0.35) | GAACTSD | |
| SCHEMBL19628400 | 0.85 | SCN9A (0.35) | GAA | |
| SCHEMBL16605410 | 0.83 | GAA (0.36) | GAACTSDNAAA | |
| SCHEMBL17898912 | 0.83 | GAA (0.40) | GAACTSDNFKB1NFKB2RELA | |
| SCHEMBL19628420 | 0.83 | GAA (0.40) | GAANFKB1NFKB2RELANAAA | |
| SCHEMBL17898809 | 0.81 | GAA (0.39) | GAACTSD | |
| SCHEMBL19628408 | 0.81 | KDM1A (0.36) | GAANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170334934-A1 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2017-11-23 | — | — | US | disclosed |
| US-20170334934-A1 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170334934-A1 | Macrocyclic picolinamides as fungicides | CYP4F12, CYP1A2, FKBP2 | GAA 1303/4885CTSD 1352/4885NFKB1 4561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.