Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.80 |
| ▸ | LMNA | P02545 | 2/20 | 0.80 |
| ▸ | MAPT | P10636 | 2/20 | 0.80 |
| ▸ | MEN1 | O00255 | 6/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13598000 | 0.88 | KDM4E (0.88) | KDM4ELMNAMAPTMEN1KMT2A | |
| SCHEMBL13598042 | 0.78 | USP2 (0.76) | KDM4ELMNAMAPTMEN1KMT2A | |
| SCHEMBL13598035 | 0.77 | KMT2A (1.00) | KDM4ELMNAMAPTMEN1KMT2A | |
| SCHEMBL13598044 | 0.76 | KDM4E (0.70) | KDM4ELMNAMAPTMEN1KMT2A | |
| SCHEMBL13598037 | 0.76 | USP2 (0.98) | KDM4ELMNAMAPTMEN1KMT2A | |
| SCHEMBL16426639 | 0.76 | KDM4E (0.79) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL821620 | 0.75 | KMT2A (0.76) | KDM4ELMNAMAPTMEN1KMT2A | |
| SCHEMBL13598032 | 0.75 | KMT2A (1.00) | KDM4ELMNAMAPTMEN1KMT2A | |
| SCHEMBL17899111 | 0.75 | KDM4E (0.68) | KDM4ELMNAMAPTMEN1KMT2A | |
| SCHEMBL22639786 | 0.75 | USP2 (1.00) | KDM4ELMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10266527-B2 | T-box riboswitch-binding anti-bacterial compounds | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF ALBANY (US) | 2019-04-23 | — | — | US | disclosed |
| US-20160194317-A1 | T-BOX RIBOSWITCH-BINDING ANTI-BACTERIAL COMPOUNDS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2016-07-07 | — | — | US | disclosed |
| US-20160194317-A1 | T-BOX RIBOSWITCH-BINDING ANTI-BACTERIAL COMPOUNDS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2016-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10266527-B2 | T-box riboswitch-binding anti-bacterial compounds | TARBP1, AARS1, NSUN3 | KDM4E 2123/4885LMNA 4231/4885MAPT 4117/4885 |
| US-20160194317-A1 | T-BOX RIBOSWITCH-BINDING ANTI-BACTERIAL COMPOUNDS | TARBP1, AARS1, NSUN3 | KDM4E 2123/4885LMNA 4231/4885MAPT 4117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.