Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 6/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16426639 | 0.93 | KDM4E (0.79) | KDM4ELMNAMEN1KMT2ATSHR | |
| SCHEMBL38659448 | 0.81 | MEN1 (0.73) | KDM4ELMNAMEN1KMT2APOLB | |
| SCHEMBL38660692 | 0.79 | MEN1 (0.76) | KDM4ELMNAMEN1KMT2APOLB | |
| SCHEMBL38659938 | 0.76 | MEN1 (0.68) | KDM4ELMNAMEN1KMT2APOLB | |
| SCHEMBL10674767 | 0.76 | MEN1 (1.00) | KDM4ELMNAMEN1KMT2AUSP2 | |
| SCHEMBL13726550 | 0.76 | SMN1; SMN2 (0.70) | KDM4ELMNAMEN1KMT2APOLB | |
| SCHEMBL17899115 | 0.75 | KDM4E (0.80) | KDM4ELMNAMEN1KMT2APOLB | |
| SCHEMBL38659614 | 0.75 | TDP1 (0.75) | KDM4ELMNAMEN1KMT2APOLB | |
| SCHEMBL6950902 | 0.75 | HSD17B10 (0.51) | KDM4EMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12869734 | 0.75 | MEN1 (0.84) | KDM4ELMNAMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10266527-B2 | T-box riboswitch-binding anti-bacterial compounds | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF ALBANY (US) | 2019-04-23 | — | — | US | disclosed |
| US-20160194317-A1 | T-BOX RIBOSWITCH-BINDING ANTI-BACTERIAL COMPOUNDS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2016-07-07 | — | — | US | disclosed |
| US-20160194317-A1 | T-BOX RIBOSWITCH-BINDING ANTI-BACTERIAL COMPOUNDS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2016-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10266527-B2 | T-box riboswitch-binding anti-bacterial compounds | TARBP1, AARS1, NSUN3 | KDM4E 2123/4885LMNA 4231/4885MEN1 4763/4885 |
| US-20160194317-A1 | T-BOX RIBOSWITCH-BINDING ANTI-BACTERIAL COMPOUNDS | TARBP1, AARS1, NSUN3 | KDM4E 2123/4885LMNA 4231/4885MEN1 4763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.